Structure and Reactivity

Author: Ivano Bertini

Publisher: University Science Books

ISBN: 9781891389436

Category: Science

Page: 739

View: 460

The long awaited text for 21st century courses in biological inorganic chemistry is now available. Organized and edited by Ivano Bertini, Harry Gray, Ed Stiefel, and Joan Valentine, with contributions from many other world leaders in the field, this all-new book is equally appropriate for graduate or senior undergraduate courses in bioinorganic chemistry. The book has been extensively class-tested at Princeton and UCLA, and it includes tutorials in biology and biochemistry and in inorganic chemistry to aid students of varying backgrounds. The main text is divided into two parts. Part A, 'Overviews of Biological Inorganic Chemistry', sets forth the unifying principles of the field. A full course in bioinorganic chemistry could be based entirely on this overview section, which is a really a book within a book! Part B, 'Metal-Ion Containing Biological Systems', describes specific classes of systems in detail. A special feature is the strong connection to the genomic revolution that has dramatically enhanced our ability to define the function of gene products in living organisms. Throughout the book, protein data bank codes are given for structures discussed in the text, and students are encouraged to learn to use the PDB in their courses and research.
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Chemistry, Inorganic chemistry

Author: CTI Reviews

Publisher: Cram101 Textbook Reviews

ISBN: 1490297553

Category: Education

Page: 66

View: 2350

Facts101 is your complete guide to Biological Inorganic Chemistry, Structure and Reactivity. In this book, you will learn topics such as as those in your book plus much more. With key features such as key terms, people and places, Facts101 gives you all the information you need to prepare for your next exam. Our practice tests are specific to the textbook and we have designed tools to make the most of your limited study time.
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Prinzipien von Struktur und Reaktivität

Author: James Huheey,Ellen Keiter,Richard Keiter

Publisher: Walter de Gruyter GmbH & Co KG

ISBN: 3110307952

Category: Science

Page: 1340

View: 4818

This modern textbook stands out from other standard textbooks. The framework for the learning units is based on fundamental principles of inorganic chemistry, such as symmetry, coordination, and periodicity. Specific examples of chemical reactions are presented to exemplify and demonstrate these principles. Numerous new illustrations, a new layout, and large numbers of exercises following each chapter round out this new edition.
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Author: Ines Batinić-Haberle,Júlio S. Rebouças,Ivan Spasojević

Publisher: Springer

ISBN: 3319307053

Category: Science

Page: 694

View: 2018

This essential volume comprehensively discusses redox-active therapeutics, focusing particularly on their molecular design, mechanistic, pharmacological and medicinal aspects. The first section of the book describes the basic aspects of the chemistry and biology of redox-active drugs and includes a brief overview of the redox-based pathways involved in cancer and the medical aspects of redox-active drugs, assuming little in the way of prior knowledge. Subsequent sections and chapters describe more specialized aspects of central nervous system injuries, neurodegenerative diseases, pain, radiation injury and radioprotection (such as of brain, lungs, head and neck and erectile function) and neglected diseases (e.g., leishmaniasis). It encompasses several major classes of redox-active experimental therapeutics, which include porphyrins, salens, nitrones, and most notably metal-containing (e.g., Mn, Fe, Cu, Zn, Sb) drugs as either single compounds or formulations with nanomaterials and quantum dots. Numerous illustrations, tables and figures enhance and complement the text; extensive references to relevant literature are also included. Redox-Active Therapeutics is an invaluable addition to Springer’s Oxidative Stress in Applied Basic Research and Clinical Practice series. It is essential reading for researchers, clinicians and graduate students interested in understanding and exploring the Redoxome—the organism redox network—as an emerging frontier in drug design, redox biology and medicine.
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Author: Duward F. Shriver,Peter W. Atkins,Cooper H. Langford

Publisher: John Wiley & Sons

ISBN: 9783527292509

Category: Science

Page: 909

View: 2068

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Author: Kurt Peter C. Vollhardt,Neil Eric Schore

Publisher: John Wiley & Sons

ISBN: 3527327541

Category: Chemistry, Organic

Page: 1452

View: 3227

Besser Konzepte und Ideen der organischen Chemie verstehen, als eine Vielzahl von Fakten auswendig beherrschen! Diesem Motto bleibt der "Vollhardt/Schore" auch in der neuesten Auflage treu. Das neu gestaltete Layout, beispielhaft gelöste Übungsaufgaben und die deutlich erweiterten Verständnisübungen führen einprägsam an die Methodik zur Lösung organisch-chemischer Probleme heran. So werden nicht nur die stofflichen Grundlagen der organischen Chemie, sondern auch das "Gewusst wie" fast schon spielerisch vermittelt. Nicht nur für Chemiestudenten, auch für Biochemiker, Pharmazeuten, Biologen und Mediziner ist der "Vollhardt/Schore" der fachliche Grundstock für die organische Chemie.
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Author: Werner Massa

Publisher: Springer-Verlag

ISBN: 3835190938

Category: Science

Page: 266

View: 7849

In anschaulicher Form - unterstützt durch zahlreiche Abbildungen - führt dieses Lehrbuch in die Kristallstrukturbestimmung ein. Die kristallographischen Grundlagen und einzelne praktische Schritte der modernen Kristallstrukturbestimmung werden verständlich und nachvollziehbar erklärt.
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A New Introduction to Molecular Structure and Function

Author: Robert R. Crichton

Publisher: Academic Press

ISBN: 0128117427

Category: Science

Page: 692

View: 6234

Biological Inorganic Chemistry: A New Introduction to Molecular Structure and Function, Third Edition, provides a comprehensive discussion of the biochemical aspects of metals in living systems. The fascinating world of the role of metals in biology, medicine and the environment has progressed significantly since the very successful Second Edition of the book published in 2012. Beginning with an overview of metals and selected nonmetals in biology, the book supports the interdisciplinary nature of this vibrant area of research by providing an introduction to basic coordination chemistry for biologists and structural and molecular biology for chemists. Having built this accessible foundation, the book progresses to discuss biological ligands for metal ions, intermediary metabolism and bioenergetics, and methods to study metals in biological systems. The book also covers metal assimilation pathways; transport, storage, and homeostasis of metal ions; sodium and potassium channels and pumps; magnesium phosphate metabolism and photoreceptors; calcium and cellular signaling; the catalytic role of several classes of mononuclear zinc enzymes; the biological chemistry of iron; and copper chemistry and biochemistry. In addition, the book discusses nickel and cobalt enzymes; manganese chemistry and biochemistry; molybdenum, tungsten, vanadium, and chromium; non-metals in biology; biomineralization; metals in the brain; metals and neurodegeneration; metals in medicine and metals as drugs; and metals in the environment. Now in its Third Edition, this popular and award-winning resource highlights recent exciting advances and provides a thorough introduction for both researchers approaching the field from a variety of backgrounds, as well as advanced students. Includes a thorough survey of metals in biological systems: in the human body, in medicine and in the environment Previous winner (Second Edition) of the 2013 Textbook Excellence Award (Texty) from the Text and Academic Authors Association Features new sections: an overview of the different functions of essential metal ions; toxic metals in diagnosis and therapeutics; crystal and ligand field theory and their limitations; molecular orbital theory; genetic and molecular biological approaches to study metals; more complex cofactors and their biosynthesis; photosynthetic oxidation of water; man-made environmental pollution; and metals as poisons
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Im Reich der Elemente

Author: Sam Kean

Publisher: Hoffmann und Campe

ISBN: 3455850030

Category: Psychology

Page: 448

View: 398

Woraus besteht die Welt, woraus Mikroben, Meere, der Mensch? Kean gelingt etwas Schönes: Man kapiert’s auch ohne dröge Formeln. Das Hauptgebäude der modernen Chemie, das Periodensystem der Elemente, sieht langweilig aus, doch in ihm verbergen sich spannende Geschichten über Alchimisten, Entdecker und Goldgräber, Medizinalräte und Quacksalber, Kriegsstrategen, Spione, Geschäftemacher und Spinner. So macht Naturwissenschaft Spaß! Das periodische System der Elemente ist nicht nur eine große wissenschaftliche Leistung, sondern auch eine Schatzkiste voller skurriler Episoden, die von Leidenschaft, Abenteuern, Betrug und Besessenheit handeln. Während Kean die Grundbausteine des Universums und die Ordnung, die sie schaffen, erklärt, erzählt er zugleich, welche Rolle sie vom Urknall bis heute gespielt haben. Wie etwa Gerhard Domagk das Leben seiner Tochter riskierte, um die ersten Antibiotika zu entwickeln. Wie Portugal sowohl den Nazis als auch den Alliierten zu astronomischen Preisen Wolfram lieferte, weil beide Seiten es dringend für den Krieg brauchten.
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Author: Catherine E. Housecroft,Alan G. Sharpe,Annette Rompel

Publisher: N.A

ISBN: 9783827371928

Category: Anorganische Chemie - Lehrbuch

Page: 1013

View: 2851

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Author: Gérard Jaouen,Nils Metzler-Nolte

Publisher: Springer Science & Business Media

ISBN: 3642131840

Category: Science

Page: 294

View: 431

Contents: Gérard Jaouen, Nils Metzler-Nolte : Introduction ; Stéphane GIBAUD and Gérard JAOUEN: Arsenic - based drugs: from Fowler’s solution to modern anticancer chemotherapy; Ana M. Pizarro, Abraha Habtemariam and Peter J. Sadler : Activation Mechanisms for Organometallic Anticancer Complexes; Angela Casini, Christian G. Hartinger, Alexey A. Nazarov, Paul J. Dyson : Organometallic antitumour agents with alternative modes of action; Elizabeth A. Hillard, Anne Vessières, Gerard Jaouen : Ferrocene functionalized endocrine modulators for the treatment of cancer; Megan Hogan and Matthias Tacke : Titanocenes – Cytotoxic and Anti-Angiogenic Chemotherapy Against Advanced Renal-Cell Cancer; Seann P. Mulcahy and Eric Meggers : Organometallics as Structural Scaffolds for Enzyme Inhibitor Design; Christophe Biot and Daniel Dive : Bioorganometallic Chemistry and Malaria; Nils Metzler-Nolte : Biomedical applications of organometal-peptide conjugates; Roger Alberto : Organometallic Radiopharmaceuticals; Brian E. Mann : Carbon Monoxide – an essential signaling molecule.
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Author: Marie Curie

Publisher: BoD – Books on Demand

ISBN: 3845722223

Category: Science

Page: 144

View: 7287

Marie Sklodowska Curie, Trägerin des Nobelpreises für Physik und für Chemie, untersuchte die von Henri Becquerel beobachtete Strahlung von Uranverbindungen. Gemeinsam mit ihrem Mann Pierre entdeckte sie das Radium und das Polonium und prägte den Begriff „radioaktiv“. Ihre Forschungsergebnisse fasste sie in ihrer hier vorliegenden Dissertation zusammen, die innerhalb eines Jahres in fünf Sprachen übersetzt wurde. Sorgfältig bearbeiteter Nachdruck der deutschsprachigen Ausgabe aus dem Jahr 1904.
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Author: Robert R. Crichton,Ricardo O. Louro

Publisher: Newnes

ISBN: 0444563598

Category: Science

Page: 336

View: 835

The book reviews the use of spectroscopic and related methods to investigate the complex structures and mechanisms of biological inorganic systems that contain metals. Each chapter presents an overview of the technique including relevant theory, clearly explains what it is and how it works and then presents how the technique is actually used to evaluate biological structures. Practical examples and problems are included to illustrate each technique and to aid understanding. Designed for students and researchers who want to learn both the basics, and more advanced aspects of bioinorganic chemistry. Many colour illustrations enable easier visualization of molecular mechanisms and structures Worked examples and problems are included to illustrate and test the reader’s understanding of each technique Written by a multi-author team who use and teach the most important techniques used today to analyse complex biological structures
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Author: Harry B. Gray

Publisher: Walter de Gruyter

ISBN: 3110830620

Category: Reference

Page: 205

View: 8819

“Electrons and chemical bonding: This standard textbook on quantum chemistry is easy to understand even for chemists; its basic concepts never become obsolete. Well done didactically, concise and to-the-point.” Prof. Dr. Ralf Steudel, TU Berlin
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Author: Ingo-Peter Lorenz,Norbert Kuhn,Stefan Berger,Dines Christen

Publisher: Walter de Gruyter GmbH & Co KG

ISBN: 311036493X

Category: Science

Page: 260

View: 3779

Basierend auf einem Kompaktkurs, bringt dieses Buch den Studenten der Chemie die grundlegenden Konzepte der Molekülsymmetrie, Symmetrieoperationen und Punktgruppen nahe und behandelt Schwingungs- und Elektronenspektroskopie, sowie Kernmagnetische Resonanz. Im Rahmen der Diskussion werden sowohl spektroskopische Befunde mit Hilfe der Molekülsymmetrie erklärt, als auch aus Messdaten Informationen zur Molekülsymmetrie abgeleitet.
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From Biology to Biotechnology and Medical Application

Author: Edmund Bäuerlein

Publisher: Wiley-VCH

ISBN: 9783527299874

Category: Science

Page: 316

View: 6704

Teeth, bones, kidney stones, and skeletons of algae, mussels, and grasses: all examples of biomineralization. Whole mountains owe their existence to the ability of organisms to mineralize in their cells inorganic compounds from solutions. Those minerals made by organisms are used for various purposes. Some of these minerals are magnetic and therefore of interest to nanotechnology. Thus there is a rapidly growing number of research groups and journals worldwide dealing with biomineralization. This book provides a much-needed up-to-date account of the important developments in biomineralization, focusing on investigations of unicellular organisms. An international and interdisciplinary team of authors, under the direction of a leading expert in the field, presents research results from first-hand experience as well as general information and a full list of references. Specific applications, such as the use of biominerals as contrast agents in cancer therapy, the templated crystallization of colloids, and in nanotechnology are highlights of this book.
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Volume 20: Concepts on Metal Ion Toxicity

Author: Helmut Sigel

Publisher: CRC Press

ISBN: 9780824775407

Category: Science

Page: 416

View: 4480

Metal Ions in Biological Systems is devoted to increasing our understanding of the relationship between the chemistry of metals and life processes. The volumes reflect the interdisciplinary nature of bioinorganic chemistry and coordinate the efforts of researchers in the fields of biochemistry, inorganic chemistry, coordination chemistry, environmental chemistry, biophysics, pharmacy, and medicine. Volumes deal with such topics as the formation, stability, structure, and reactivity of biological compounds of low and high molecular weight containing metal ions; the metabolism and transport of metal ions and their complexes; and new models of complicated natural structures and processes. Volume 21 describes the underlying theories of nuclear magnetic resonance (NMR), promoting a wider use of NMR in studies of paramagnetic species. In six concise chapters by leading international authorities, Applications of Nuclear Magnetic Resonance to Paramagnetic Species outlines the most recent developments regarding the use of nuclear relaxation as a source for structural information ... examines studies of magnetically coupled metalloproteins and metal-porphyrin induced dipolar shifts for conformational analysis ... and evaluates the potential of paramagnetic ions as agents for enhancing NMR image contrast. With over 500 references that facilitate further research, Applications of Nuclear Magnetic Resonance to Paramagnetic Species is an essential resource for scientists and students in such disciplines as biophysics; bioinorganic, inorganic, and coordination chemistry; biochemistry; molecular biology; and enzymology. Book jacket.
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Author: Edward I. Solomon,Robert A. Scott,R. Bruce King

Publisher: John Wiley & Sons

ISBN: 111861724X

Category: Science

Page: 616

View: 4109

Over the past several decades there have been major advances in ourability to computationally evaluate the electronic structure ofinorganic molecules, particularly transition metal systems. Thisadvancement is due to the Moore’s Law increase in computingpower as well as the impact of density functional theory (DFT) andits implementation in commercial and freeware programs for quantumchemical calculations. Improved pure and hybrid density functionalsare allowing DFT calculations with accuracy comparable tohigh-level Hartree-Fock treatments, and the results of thesecalculations can now be evaluated by experiment. When calculations are correlated to, and supported by,experimental data they can provide fundamental insight intoelectronic structure and its contributions to physical propertiesand chemical reactivity. This interplay continues to expand andcontributes to both improved value of experimental results andimproved accuracy of computational predictions. The purpose of this EIC Book is to provide state-of-the-artpresentations of quantum mechanical and related methods and theirapplications, written by many of the leaders in the field. Part 1of this volume focuses on methods, their background andimplementation, and their use in describing bonding properties,energies, transition states and spectroscopic features. Part 2focuses on applications in bioinorganic chemistry and Part 3discusses inorganic chemistry, where electronic structurecalculations have already had a major impact. This addition to theEIC Book series is of significant value to both experimentalistsand theoreticians, and we anticipate that it will stimulate bothfurther development of the methodology and its applications in themany interdisciplinary fields that comprise modern inorganic andbioinorganic chemistry. This volume is also available as part of Encyclopedia ofInorganic Chemistry, 5 Volume Set. This set combines all volumes published as EIC Books from 2007to 2010, representing areas of key developments in the field ofinorganic chemistry published in the Encyclopedia of InorganicChemistry. ahref="http://eu.wiley.com/WileyCDA/WileyTitle/productCd-1119994284.html"Findout more/a.
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Author: Francis A. Carey,Richard J. Sundberg

Publisher: John Wiley & Sons

ISBN: 9783527292172

Category: Science

Page: 1635

View: 7908

Endlich gibt es ein weiterführendes Lehrbuch der Organischen Chemie in deutscher Sprache! Es wird die Studenten auf den Gebieten Reaktionsmechanismen, Stereochemie und insbesondere Organische Synthese bis zum Diplom begleiten, und darüber hinaus ist es ein äußerst nützliches Nachschlagewerk auch für Diplomanden und Doktoranden. Die deutsche Ausgabe wurde gegenüber dem Original nochmals erweitert und aktualisiert. Erste Dozentenstimmen: 'Die erste deutsche Ausgabe des Carey/Sundberg erfüllt alle Erwartungen an ein modernes Lehrbuch der Organischen Chemie.' - 'Es ist zur Zeit das beste Lehrbuch der Organischen Chemie und unentbehrlich für fortgeschrittene Studenten, Diplomanden und Doktoranden.' - 'Endlich! Ich empfehle dieses Buch bereits seit Jahren fortgeschrittenen Studenten.' - 'Es ist bezeichnend, daß es immer besonders motivierte und leistungsstarke Studenten waren, die mich fragten, ob ich ihnen den Carey/Sundberg empfehlen kann. Ich kann es.' - 'Endlich wird es ein ausgewogenes Lehrbuch zur Organischen Chemie für Fortgeschrittene in deutscher Sprache geben. Die Kompetenz der Herausgeber bürgt für hohen Standard.'
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