Author: N.A

Publisher: Elsevier

ISBN: 9780080858531

Category: Science

Page: 775

View: 7678

Ion Chromatography
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Chromatography, Bioconjugation, and Protein Stability

Author: David Pfister,Lucrèce Nicoud,Massimo Morbidelli

Publisher: Cambridge University Press

ISBN: 1108420222

Category: Medical

Page: 347

View: 5852

Provides a coherent and critical view on the potential benefits of various continuous processes in the biopharmaceutical industry.
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Author: Y. H. Hui,Frank Sherkat

Publisher: CRC Press

ISBN: 146650787X

Category: Technology & Engineering

Page: 3632

View: 8875

Advances in food science, technology, and engineering are occurring at such a rapid rate that obtaining current, detailed information is challenging at best. While almost everyone engaged in these disciplines has accumulated a vast variety of data over time, an organized, comprehensive resource containing this data would be invaluable to have. The Handbook of Food Science, Technology, and Engineering, 4 Volume Set is that resource, presenting the latest information available in a thorough, straightforward format.
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From Diagnosis to Therapy

Author: Jennifer E. Van Eyk,Michael J. Dunn

Publisher: John Wiley & Sons

ISBN: 3527622160

Category: Science

Page: 694

View: 788

Unparalleled in its scope and depth, this book brings together proteomic approaches in diagnosis and treatment from all clinical fields, including clinical toxicology. The result is a new discipline in molecular medicine that will revolutionize the treatment and prevention of cancer, stroke and other severe diseases. Following an overview of clinical proteomics, the authors look at the technologies available, before moving on to cancer, cardiopulmonary disease, diabetes and stroke. A whole section is devoted to toxicity and the work is rounded off with a discussion of the future of clinical proteomics.
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Author: Danilo Corradini,Elena Eksteen (Katz),Roy Eksteen,Peter Schoenmakers,Neil Miller

Publisher: CRC Press

ISBN: 9780203909751

Category: Science

Page: 1008

View: 4389

Delineating its usage in separation, purification and detection processes across a variety of disciplines, from industry to applied research, this work discusses the principles, techniques and instrumentation involving HPLC within a detailed framework. Over 100 tables present previously scattered experimental data.
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Author: Leo M.L. Nollet,Leen S. P. De Gelder

Publisher: CRC Press

ISBN: 9780849384868

Category: Technology & Engineering

Page: 944

View: 3919

This work details water sampling and preservation methods by enumerating the different ways to measure physical, chemical, organoleptical, and radiological characteristics. It provides step-by-step descriptions of separation, residue determination, and cleanup techniques for a variety of fresh- and salt-waters. It also discusses information regarding the analysis and detection of bacteria and algae.
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Bibliography section. A

Author: N.A

Publisher: N.A

ISBN: N.A

Category: Chromatographic analysis

Page: N.A

View: 1014

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Author: Hugh M. Cartwright

Publisher: Oxford University Press on Demand

ISBN: N.A

Category: Computers

Page: 205

View: 1347

' This area is an intellectually active one that has inspired many research students, not only in chemistry but also engineering, biology and computer science. This book certainly is a useful and valuable reference, written exactly at the level that a computationally literate graduate student can take home, read and find out what is what before deciding whether to delve deeper' Chemistry and IndustryThis is a fundamental reference work for any scientist contemplating using AI for data analysis.
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Author: Herman F. Mark

Publisher: Wiley-Interscience

ISBN: 9780471288244

Category: Technology & Engineering

Page: 3005

View: 3343

This completely new Third Edition of the Mark Encyclopedia of Polymer Science and Technology brings the state-of-the-art to the 21st century, with coverage of nanotechnology, new imaging and analytical techniques, new methods of controlled polymer architecture, biomimetics, and more. Whereas earlier editions published one volume at a time, the third edition is being published in 3 Parts of 4 volumes each. Each of these 4-volume Parts is an A-Z selection of the latest in polymer science and technology as published in the updated online edition of the Mark Encyclopedia of Polymer Science and Technology (available at www.mrw.interscience.wiley.com/epst). Order the 12 volume set (ISBN 0471275077) now for the best value and receive each of the 4 volume Parts as they publish. The complete list of titles to appear in Part 1 of this new third print edition can be viewed at www.mrw.interscience.wiley.com/epst and clicking on "What's New". Check this website often as new articles are added periodically.
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Author: James P. Landers

Publisher: CRC

ISBN: 9780849386909

Category: Medical

Page: 649

View: 3026

The Handbook of Capillary Electrophoresis is a valuable collection of in-depth discussions of specific areas of capillary electrophoresis (CE) that are key to the practical use of CE for sample analysis. The handbook is divided into five parts. Part I focuses on various modes of CE that have been developed and applied to analytical/separation problems. Part II covers detection in CE, with one section reviewing all detector systems that have been successfully interfaced with CE and another that focuses on CE-mass spectrometry. Part III explores how CE can be applied to the analysis of a specific class of molecules/analytes or to solving separation problems. CE analysis of organic ions, pharmaceuticals, glycoconjugates, peptides, proteins, and DNA fragments; the components of single cells; and the utility of capillary coatings in CE are all covered in this section. A key element of this handbook is its discussion of the potential role of CE for solving clinical problems and the potential for CE and CE-MS to advance analysis of drug metabolism. The handbook also presents practical and theoretical discussions on various aspects of CE, including sample matrix and its effects on separation, the need for controlling capillary temperature, and the present and future implications of EOF control. In-depth discussions of this nature comprise Parts IV and V. The Handbook of Capillary Electrophoresis will be an outstanding reference for analytical chemists, biochemists, clinical chemists, cell biologists, and pharmaceutical researchers.
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Author: Herman Francis Mark

Publisher: Wrox

ISBN: 9780470046104

Category: Science

Page: 1462

View: 5741

The compact, affordable reference, revised and updated The Encyclopedia of Polymer Science and Technology, Concise Third Edition provides the key information from the complete, twelve-volume Mark's Encyclopedia in an affordable, condensed format. Completely revised and updated, this user-friendly desk reference offers quick access to all areas of polymer science, including important advances in nanotechnology, imaging and analytical techniques, controlled polymer architecture, biomimetics, and more, all in one volume. Like the twelve-volume full edition, the Encyclopedia of Polymer Science and Technology, Concise Third Edition provides both SI and common units, carefully selected key references for each article, and hundreds of tables, charts, figures, and graphs.
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Principles, High Resolution Methods, and Applications

Author: Jan-Christer Janson

Publisher: John Wiley & Sons

ISBN: 1118002199

Category: Science

Page: 532

View: 2230

The authoritative guide on protein purification—now completely updated and revised Since the Second Edition of Protein Purification was published in 1998, the sequencing of the human genome and other developments in bioscience have dramatically changed the landscape of protein research. This new edition addresses these developments, featuring a wealth of new topics and several chapters rewritten from scratch. Leading experts in the field cover all major biochemical separation methods for proteins in use today, providing professionals in biochemistry, organic chemistry, and analytical chemistry with quick access to the latest techniques. Entirely new or thoroughly revised content includes: High-resolution reversed-phase liquid chromatography Electrophoresis in gels Conventional isoelectric focusing in gel slabs and capillaries and immobilized pH gradients Affinity ligands from chemical and biological combinatorial libraries Membrane separations Refolding of inclusion body proteins from E. coli Purification of PEGylated proteins High throughput screening techniques in protein purification The history of protein chromatography
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Author: Lokesh Bhattacharyya,Jeffrey S. Rohrer

Publisher: John Wiley & Sons

ISBN: 1118146999

Category: Medical

Page: 448

View: 5699

This is a comprehensive source of information on the application of ion chromatography (IC) in the analysis of pharmaceutical drugs and biologicals. This book, with contributors from academia, pharma, the biotech industry, and instrument manufacturing, presents the different perspectives, experience, and expertise of the thought leaders of IC in a comprehensive manner. It explores potential IC applications in different aspects of product development and quality control testing. In addition, an appendix section gives information on critical physical and chromatographic parameters related to IC and information on current manufacturers of IC systems, columns, and other components.
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Author: Robert J. Flanagan,Andrew A. Taylor,Ian D. Watson,Robin Whelpton

Publisher: John Wiley & Sons

ISBN: 0470516283

Category: Science

Page: 544

View: 2185

The analytical toxicologist may be required to detect, identify, and in many cases measure a wide variety of compounds in samples from almost any part of the body or in related materials such as residues in syringes or in soil. This book gives principles and practical information on the analysis of drugs and poisons in biological specimens, particularly clinical and forensic specimens. After providing some background information the book covers aspects of sample collection, transport, storage and disposal, and sample preparation. Analytical techniques - colour tests and spectrophotometry, chromatography and electrophoresis, mass spectrometry, and immunoassay – are covered in depth, and a chapter is devoted to the analysis of trace elements and toxic metals. General aspects of method implementation/validation and laboratory operation are detailed, as is the role of the toxicology laboratory in validating and monitoring the performance of point of care testing (POCT) devices. The book concludes with reviews of xenobiotic absorption, distribution and metabolism, pharmacokinetics, and general aspects of the interpretation of analytical toxicology results. A clearly written, practical, integrated approach to the basics of analytical toxicology. Focuses on analytical, statistical and pharmacokinetic principles rather than detailed applications. Assumes only a basic knowledge of analytical chemistry. An accompanying website provides additional material and links to related sites. Written by an experienced team of authors,Fundamentals of Analytical Toxicology is an invaluable resource for those starting out in a career in analytical toxicology across a wide range of disciplines including clinical and forensic science, food safety, and pharmaceutical development. Praise from the reviews: “This is an ambitious effort to describe in detail the many and varied aspects of the science of toxicological analysis. The 17 chapters cover every foreseeable aspect, from specimen collection through analytical techniques and quality control to pharmacological principles and interpretation of results. The authors bring together a great deal of experience in the field and have succeeded admirably in achieving their goal: "to give principles and practical information on the analysis of drugs, poisons and other relevant analytes in biological specimens...". The book is very readable and quite up-to-date, and contains many illustrative figures, charts and tables. Both the student and the practicing professional would do well to study this material carefully, as there is something here for every conceivable level of interest.” Review from Randall Baselt "This text comes highly recommended for any analytical toxicology trainee." The Bulletin of the Royal College of Pathologists “Overall, this book provides a comprehensive, thorough, clear, up to date and practical treatment of analytical toxicology at a high standard. Understanding of the text is enhanced by the use of many illustrations. Specifications, guidelines, and methods are highlighted in grey background “Boxes”. The many and up to date literature references in each chapter demonstrate the authors’ thorough work and permit easy access to deeper information. Therefore this book can be highly recommended as a valuable source of knowledge in analytical toxicology both as an introduction and for the advanced reader.” GTFCh Bulletin “Toxichem + Krimtech”, May 2008 (translated, original review in German) “Many toxicologists will add this important reference to their libraries because it competently fills a need ...” International Journal of Toxicology
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Author: M. Kastner

Publisher: Elsevier

ISBN: 0080858694

Category: Science

Page: 933

View: 2736

Protein Liquid Chromatography is a handbook-style guide to liquid chromatography as a tool for isolating and purifying proteins, consisting of 25 individual chapters divided into three parts: Part A covers commonly-used, classic modes of chromatography such as ion-exchange, size-exclusion, and reversed-phase; Part B deals with various target protein classes such as membrane proteins, recombinant proteins, and glycoproteins; and Part C looks at various miscellaneous related topics, including coupling reaction, buffer solution additives, and software. The text as a whole can be viewed as a systematic survey of available methods and how best to use them, but also attempts to provide an exhaustive coverage of each facet. How to solve a specific problem using a chosen method is the overall essence of the volume. The principle philosophy of this compilation is that practical application is everything; therefore, both classical and modern methods are presented in detail, with examples involving conventional, medium- and high-pressure techniques. Over-exposure to history, concept, and theory has deliberately been avoided. The reader will find a wealth of tips and tricks from users for users, including advice on the advantages and disadvantages of each method. Easy-to-read sections on "Getting started now" and "Where to go from here" attempt to provide hands-on, fool-proof detailed practical procedures with complete and even standard model runs for any scientist or technician at work in this area.
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Author: Randy D. Down,Jay H. Lehr

Publisher: John Wiley & Sons Inc

ISBN: N.A

Category: Science

Page: 1068

View: 9700

This is handbook will serve as a valuable guide in the application of new and emerging engvironmental instrumentation and control technologies to meet current and future regulatory requirements.
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Author: Ira S. Krull

Publisher: CRC Press

ISBN: 9780824775797

Category: Science

Page: 376

View: 6503

The first book to focus entirely on reactions for analyte detection and characterization, Reaction Detection in Liquid Chromatography depicts off- and on-line, pre- and post-column approaches that have been successfully used for many classes of compounds, both organic and inorganic, in high performance liquid chromatography. The book gives special attention to methods and instrumentation associated with post-column reaction detection, discussing theory, background, principles, and equations ... and also highlights major areas of reaction chemistry, such as immobilized (or solution) enzymatic reactions, homogenous solution chemistry, photochemical derivation, pairedion reagents, solid phase and solid supported reagents, and reactions for inorganic species. In addition, Reaction Detection in Liquid Chromatography details the efficiencies of the various reactions surveyed ... forecasts how the utility of each reaction is likely to be enhanced by new research ... and gives data that will allow the reader to reproduce reaction-detection approaches for new analytes and samples. Reaction Detection in Liquid Chromatography is essential reading for analytical, bioanalytical, quality control, and research and development chemists. It also comprises a fine reference for analysts involved in development and applications of liquid chromatography for specific qualitative and quantitative analyte identification; and in-house, professional seminars. Book jacket.
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Author: Shuichi Yamamoto,Kazahiro Nakanishi,Ryuichi Matsuno

Publisher: CRC Press

ISBN: 9780824779030

Category: Science

Page: 401

View: 4167

Showing chemists how to predict ion-exchange chromatography (IEC) separation behavior and how to determine appropriate operating conditions, this reference illustrates procedures, apparatus, and types of ion exchangers, emphasizing the design and application of large-scale IEC. Complete with more than 100 useful tables and diagrams, Ion-Exchange Chromatography of Proteins explains the effects of each variable on separation behavior ... compares models and equations describing separation behavior of proteins in IEC with experimental results ... introduces design calculation procedures for scale up, adapting IEC for individual requirements ... discusses parameters affecting separation behavior, including adsorption equilibria, stationary phase diffusion, and axial dispersion ... provides examples of the most up-to-date applications, such as high- or medium-performance IEC and large-scale operations ... and reviews both theoretical and experimental literature. Ion-Exchange Chromatography of Proteins serves as an important reference for analytical, agricultural, food, and pharmaceutical chemists, chromatographers, food scientists and technologists, biochemists, and biotechnologists. Book jacket.
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