Author: Howard Maskill

Publisher: Oxford University Press

ISBN: 9780198558224

Category: Science

Page: 96

View: 6232

Focusing on organic reactions, this text begins by introducing modern technology, definitions, and concepts of mechanisms and reactivity. The following four chapters are accounts of the mechanisms of four of the main classes of reactions of aliphatic compounds.
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Author: Howard Maskill

Publisher: John Wiley & Sons

ISBN: 0470994169

Category: Science

Page: 392

View: 8766

A range of alternative mechanisms can usually be postulated for most organic chemical reactions, and identification of the most likely requires detailed investigation. Investigation of Organic Reactions and their Mechanisms will serve as a guide for the trained chemist who needs to characterise an organic chemical reaction and investigate its mechanism, but who is not an expert in physical organic chemistry. Such an investigation will lead to an understanding of which bonds are broken, which are made, and the order in which these processes happen. This information and knowledge of the associated kinetic and thermodynamic parameters are central to the development of safe, efficient, and profitable industrial chemical processes, and to extending the synthetic utility of new chemical reactions in chemical and pharmaceutical manufacturing, and academic environments. Written as a coherent account of the principal methods currently used in mechanistic investigations, at a level accessible to academic researchers and graduate chemists in industry, the book is highly practical in approach. The contributing authors, an international group of expert practitioners of the techniques covered, illustrate their contributions by examples from their own research and from the relevant wider chemical literature. The book covers basic aspects such as product analysis, kinetics, catalysis, and investigation of reactive intermediates. It also includes material on significant recent developments, e.g. computational chemistry, calorimetry, and electrochemistry, in addition to topics of high current industrial relevance, e.g. reactions in multiphase systems, and synthetically useful reactions involving free radicals and catalysis by organometallic compounds.
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Author: Ian Fleming

Publisher: Oxford University Press, USA

ISBN: 0199680906

Category: Addition reactions

Page: 118

View: 1779

Key texts in the renowned Oxford Chemistry Primers series have been fully refreshed and updated to suit the needs of today's students, lecturers, and postgraduate researchers. The rigorous and yet accessible treatment of each subject area is ideal for those wanting to know more about a particular topic not covered comprehensively in existing undergraduate texts. Moreover, cutting-edge examples and applications throughout the texts show the relevance of thechemistry being described to the real world. Pericyclic reactions constitute a fundamental class of organic chemistry, including such commercially important synthetic reactions as theDiels-Alder reaction. This primer gives a concise and accessible account of these reactions, enabling students to recognise the different types of pericyclic reaction and understand their application in organic synthesis.
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Author: Ian Fleming

Publisher: John Wiley & Sons

ISBN: 3527330690

Category: Chemical bonds

Page: 399

View: 7774

Der lang erwartete Nachfolger des Klassikers "Grenzorbitale und Reaktionen organischer Verbindungen". Die Molekülorbitalheorie wird einfach, ohne komplizierte mathematische Formeln und mit vielen illustrativen Beispielen erklärt.
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Author: Jonathan Clayden,Nick Greeves,Stuart Warren

Publisher: Springer Spektrum

ISBN: 9783642347153

Category: Science

Page: 1366

View: 7127

Ein neuer Stern am Lehrbuch-Himmel: Organische Chemie von Clayden, Greeves, Warren - der ideale Begleiter für alle Chemiestudenten. Der Schwerpunkt dieses didaktisch durchdachten, umfassenden vierfarbigen Lehrbuches liegt auf dem Verständnis von Mechanismen, Strukturen und Prozessen, nicht auf dem Lernen von Fakten. Organische Chemie entpuppt sich als dabei als ein kohärentes Ganzes, mit zahlreichen logischen Verbindungen und Konsequenzen sowie einer grundlegenden Struktur und Sprache. Dank der Betonung von Reaktionsmechanismen, Orbitalen und Stereochemie gewinnen die Studierenden ein solides Verständnis der wichtigsten Faktoren, die für alle organisch-chemischen Reaktionen gelten. So lernen sie, auch Reaktionen, die ihnen bisher unbekannt waren, zu interpretieren und ihren Ablauf vorherzusagen. Der direkte, persönliche, studentenfreundliche Schreibstil motiviert die Leser, mehr erfahren zu wollen. Umfangreiche Online-Materialien führen das Lernen über das gedruckte Buch hinaus und vertiefen das Verständnis noch weiter.
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Author: Howard Maskill

Publisher: OUP Oxford

ISBN: 9780198558200

Category: Science

Page: 100

View: 9449

This book covers areas of mechanistic and physical organic chemistry at advanced undergraduate level in a non-mathematical way. The topics included (e.g. kinetics and mechanism, catalysis, and isotope effects) are essential in any modern chemistry degree, yet are not included in standard organic chemistry text books for undergraduates. The book is thoroughly up to date and includes many examples from all areas of organic chemistry.
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Author: Andy Parsons

Publisher: John Wiley & Sons

ISBN: 1405147644

Category: Science

Page: 240

View: 6275

The development of university organic chemistry curricula and the trend towards modularisation of chemistry courses has driven the need for smaller, highly focussed and accessible organic chemistry textbooks, which complement the very detailed “standard texts”, to guide students through the key principles of the subject. This concise and accessible book provides organic chemistry notes for students studying chemistry and related courses at undergraduate level, covering core organic chemistry in a format ideal for learning and rapid revision. The material is organised so that fundamental concepts are introduced early, then built on to provide an overview of the essentials of functional group chemistry and reactivity, leading the student to a solid understanding of the basics of organic chemistry. Graphical presentation of information is central to the book, to facilitate the rapid assimilation, understanding and recall of critical concepts, facts and definitions. Students wanting a comprehensive and accessible overview of organic chemistry to build the necessary foundations for a more detailed study will find this book an ideal source of the information they require. In addition, the structured presentation, highly graphical nature of the text and practice problems with outline answers will provide an invaluable framework and aid to revision for students preparing for examinations.
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Structure, Mechanism, and Reactions

Author: Maya Shankar Singh

Publisher: John Wiley & Sons

ISBN: 3527678271

Category: Science

Page: 296

View: 3351

Most reactions in organic chemistry do not proceed in a single step but rather take several steps to yield the desired product. In the course of these multi-step reaction sequences, short-lived intermediates can be generated that quickly convert into other intermediates, reactants, products or side products. As these intermediates are highly reactive, they cannot usually be isolated, but their existence and structure can be proved by theoretical and experimental methods. Using the information obtained, researchers can better understand the underlying reaction mechanism of a certain organic transformation and thus develop novel strategies for efficient organic synthesis. The chapters are clearly structured and are arranged according to the type of intermediate, providing information on the formation, characterization, stereochemistry, stability, and reactivity of the intermediates. Additionally, representative examples and a problem section with different levels of difficulty are included for self-testing the newly acquired knowledge. By providing a deeper understanding of the underlying concepts, this is a musthave reference for PhD and Master Students in organic chemistry, as well as a valuable source of information for chemists in academia and industry working in the field. It is also ideal as primary or supplementary reading for courses on organic chemistry, physical organic chemistry or analytical chemistry.
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Author: John Jones

Publisher: Oxford University Press, USA

ISBN: 0198559593

Category: Science

Page: 86

View: 2098

The carbonyl group is the commonest functional unit of organic chemistry and a thorough understanding of its reactivity is fundamental for organic synthesis. It appears in many classes of compound, of which aldehydes, ketones, and carboxylic acid derivatives are the most important. This Primer covers the chemistry of these classes within an up-to-date mechanistic framework which embraces reactions with simple nucleophiles (hydration, acetal formation, and condensation with aminonucleophiles); enols and enolates; and their reactions with electrophiles, including alkylating agents and carbonyl groups. Core Carbonyl Chemistry is central to organic chemistry and will be invaluable to students taking chemistry or biochemistry courses at University.
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Reactions, Stereochemistry and Synthesis

Author: Reinhard Bruckner

Publisher: Springer Science & Business Media

ISBN: 3642036503

Category: Science

Page: 855

View: 1181

This English edition of a best-selling and award-winning German textbook Reaction Mechanisms: Organic Reactions · Stereochemistry · Modern Synthetic Methods is aimed at those who desire to learn organic chemistry through an approach that is facile to understand and easily committed to memory. Michael Harmata, Norman Rabjohn Distinguished Professor of Organic Chemistry (University of Missouri) surveyed the accuracy of the translation, made certain contributions, and above all adapted its rationalizations to those prevalent in the organic chemistry community in the English-speaking world. Throughout the book fundamental and advanced reaction mechanisms are presented with meticulous precision. The systematic use of red "electron-pushing arrows" allows students to follow each transformation elementary step by elementary step. Mechanisms are not only presented in the traditional contexts of rate laws and substituent effects but, whenever possible, are illustrated using practical, useful and state-of-the-art reactions. The abundance of stereoselective reactions included in the treatise makes the reader familiar with key concepts of stereochemistry. The fundamental topics of the book address the needs of upper-level undergraduate students, while its advanced sections are intended for graduate-level audiences. Accordingly, this book is an essential learning tool for students and a unique addition to the reference desk of practicing organic chemists, who as life-long learners desire to keep abreast of both fundamental and applied aspects of our science. In addition, it will well serve ambitious students in chemistry-related fields such as biochemistry, medicinal chemistry and pharmaceutical chemistry. From the reviews: "Professor Bruckner has further refined his already masterful synthetic organic chemistry classic; the additions are seamless and the text retains the magnificent clarity, rigour and precision which were the hallmark of previous editions. The strength of the book stems from Professor Bruckner’s ability to provide lucid explanations based on a deep understanding of physical organic chemistry and to limit discussion to very carefully selected reaction classes illuminated by exquisitely pertinent examples, often from the recent literature. The panoply of organic synthesis is analysed and dissected according to fundamental structural, orbital, kinetic and thermodynamic principles with an effortless coherence that yields great insight and never over-simplifies. The perfect source text for advanced Undergraduate and Masters/PhD students who want to understand, in depth, the art of synthesis ." Alan C. Spivey, Imperial College London "Bruckner’s ‘Organic Mechanisms’ accurately reflects the way practicing organic chemists think and speak about organic reactions. The figures are beautifully drawn and show the way organic chemists graphically depict reactions. It uses a combination of basic valence bond pictures with more sophisticated molecular orbital treatments. It handles mechanisms both from the "electron pushing perspective" and from a kinetic and energetic view. The book will be very useful to new US graduate students and will help bring them to the level of sophistication needed to be serious researchers in organic chemistry." Charles P. Casey, University of Wisconsin-Madison "This is an excellent advanced organic chemistry textbook that provides a key resource for students and teachers alike." Mark Rizzacasa, University of Melbourne, Australia.
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Author: Sheila R. Buxton,Stanley M. Roberts

Publisher: Springer-Verlag

ISBN: 3663098761

Category: Mathematics

Page: 264

View: 3114

Dieses Lehrbuch bietet einen Überblick über das gesamte Gebiet der Organischen Stereochemie. Der Lernenden wird von Strukturen einfacher Moleküle bis hin Biomolekülen geleitet und erhält eine ausführliche Einführung in die Begriffe und Konzepte der Stereochemie. Da diese Bestandteil vieler organischer Reaktionen ist, entscheidet auch ihr Verständnis über den Erfolg der modernen Syntheseplanung. So gehen die Autoren zum Schluß auch auf die stereochemische Kontrolle in der asymmetrischen Synthese ein. Viele klare Diagramme und Übungen mit Antworten in jedem Kapitel erleichtern das Lernen.
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Author: Dirk Steinborn

Publisher: Springer-Verlag

ISBN: 3834893757

Category: Science

Page: 434

View: 7395

Die Katalyse ist als grundlegendes Prinzip zur Überwindung der kinetischen Hemmung chemischer Reaktionen von fundamentaler Bedeutung in der Chemie und die metallorganische Komplexkatalyse ist ein Eckpfeiler der modernen Chemie. Das trifft gleichermaßen für die Grundlagen- und angewandte Forschung wie für industrielle Anwendungen zu. Ausgehend von den Prinzipien der Katalyse und den katalytisch relevanten metallorganischen Elementarschritten werden wichtige metallkomplexkatalysierte Reaktionen behandelt, wobei das mechanistische Verständnis im Vordergrund steht. Besonderer Wert wird dabei auf aktuelle Entwicklungen gelegt. Asymmetrische Synthesen finden ausführlich Berücksichtigung und an ausgewählten Beispielen wird die katalytische Wirkung von Metalloenzymen aufgezeigt. Am Beispiel der Stickstofffixierung werden die drei großen Gebiete der Katalyse – die homogene, die heterogene und die enzymatische Katalyse – vergleichend betrachtet. In der 2. Auflage ist ein neues Kapitel zur Stickstofffixierung hinzugekommen. In diesem werden vergleichend die heterogen katalysierte Reaktion, die enzymatisch katalysierte Reaktion (Nitrogenasen) sowie die homogen katalysierte Reaktion gegenübergestellt.
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Characteristics and Interconversions

Author: G. Denis Meakins

Publisher: Oxford University Press, USA

ISBN: N.A

Category: Science

Page: 92

View: 3489

The characteristic properties of functional groups and the methods for interconverting them are the foundations of organic chemistru central to all first year University organic chemistry courses. This primer will provide an extremely useful introduction to reactions of functional groups in a concise and systematic form.
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Author: Laurence M. Harwood

Publisher: Oxford University Press, USA

ISBN: 9780198556718

Category: Language Arts & Disciplines

Page: 96

View: 2697

The general principles of polar rearrangements are brought together in this undergraduate chemistry text, which deals with all the major rearrangements involving electron-deficient atoms or charged intermediates. Reactions involving migration to electron-deficient carbon, nitrogen, oxygen and sulphur, and sigmatropic rearrangements involving polar species, are thus treated in a coherent and consistent manner. Clear discussions of the reaction mechanisms are followed by examples of synthetic applications providing a concise yet comprehensive account of the nature and importance of these processes.
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Eine Einführung

Author: Helmut Günzler,Hans-Ulrich Gremlich

Publisher: John Wiley & Sons

ISBN: 3527662871

Category: Science

Page: 365

View: 9059

Die lange erwartete, vierte Auflage des Lehrbuchklassikers zur IR-Spektroskopie! Will man Substanzen eindeutig charakterisieren und auf ihre Reinheit ?berpr?fen, f?hrt kein Weg an der IR-Spektroskopie als Analysemethode vorbei. Pr?zise und leicht verst?ndlich, aktuell und sehr praxisbezogen lernen die k?nftigen Anwender alles, was sie ?ber die IR-Spektroskopie wissen m?ssen: - Aufbau und Handhabung von Spektrometern, - Vorbereitung der Proben und deren Messung, - qualitative Interpretation der Spektren, - quantitative Bestimmungen, - spezielle Anwendungsgebiete und - spezielle und verwandte Methoden. Zahlreiche Hinweise auf weiterf?hrende Literatur vermitteln eine gute Orientierung bei speziellen Fragestellungen, und helfen dabei, sich zum Experten weiterzuentwickeln.
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Author: John McMurry,Tadhg Begley

Publisher: Spektrum Akademischer Verlag

ISBN: 9783827416575

Category: Science

Page: 452

View: 8495

Oftmals mangelt es an einem Verständnis der interdisziplinären Natur von Chemie und Biologie. Dies liegt zum Teil daran, dass ein geeignetes Lehrbuch für das Grund- und Hauptstudium fehlt, das die Grundlagen hierfür schafft und als Basis für weitere Diskussionen dienen kann. Ein neues Buch von John McMurry und Tadhg Begley, prominenten Wissenschaftlern auf dem Gebiet der organischen Chemie und der mechanistischen Enzymologie, schließt elegant diese Lücke. Rongson Pongdee und Hung-wen Liu in Chemistry and Biology 2005 Vierfarbig, grundlegend, klar gegliedert, einzigartig - Für wen ist das vierfarbige Lehrbuch geeignet? Für Studenten im Grund- und Hauptstudium aus allen Bereichen der Bioorganischen Chemie und der Biologischen Chemie sowie der Chemischen Biologie und der Biochemie. - Sind Vorkenntnisse erforderlich? Nein, nur Grundkenntnisse in organischer Chemie. - Wie gliedert sich das Buch? Nach den wichtigsten biochemischen Stoffwechselwegen mit ihren Reaktionsmechanismen und der zugrunde liegenden molekularen Logik, nach denen die Natur die Moleküle des Lebens ineinander umwandelt. Die wichtigsten Stoffwechselwege der verschiedenen Hauptklassen von Biomolekülen (Lipide, Kohlenhydrate, Aminosäuren und Nucleotide) werden vorgestellt und Themen wie Ionisierungszustände, Stereochemie, Prochiralität und andere wesentliche Merkmale der Struktur und Reaktivität verständlich erklärt.
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Author: Michael J. T. Robinson

Publisher: Oxford University Press on Demand

ISBN: 9780198792758

Category: Science

Page: 89

View: 7646

This book is an account for students of how the three-dimensional shapes of molecules influence their chemical and physical properties. It begins with the structures of molecules and then describes how such structures can be changed.
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