Case Studies and Strategies from the Field
Author: Madelon L. Finkel, PhD
Publisher: Dartmouth College Press
Worldwide, cancer is responsible for one in eight deaths--more than AIDS, tuberculosis, and malaria combined. This global burden starkly illustrates the inequality between the developed and the developing world. While the majority of people living in developed countries receive timely treatment, those living in developing countries are not as fortunate and their survival rates are much lower--not only due to delays in diagnosis, but also to a lack of personnel, a paucity of treatment facilities, and the unavailability of many medications. Routine screening--a mainstay in the developed world--could greatly increase the likelihood of identifying individuals with early stage cancers and thus reduce the number of people who present with advanced disease. This book represents a critical addition to the literature of global health studies. Focusing on cervical, breast, and oral cancers, these case studies highlight innovative strategies in cancer screening in a diverse array of developing countries. The authors discuss common issues and share how obstacles--medical, economic, legal, social, and psychological--were addressed or overcome in specific settings. Each chapter offers an empirical discussion of the nature and scope of a screening program, the methodology used, and its findings, along with a candid discussion of challenges and limitations and suggestions for future efforts.
Author: Kevin J. Harrington,Rehan Kazi,Raghav C. Dwivedi,Peter Rhys-Evans
Publisher: Byword Books Private Limited
Head and neck cancer (HNC) is a rapidly evolving field of medical science. Tremendous progress has been made over the past five decades in revealing the basic molecular biology involved in the disease process, developing and adopting more effective organ-preserving treatment protocols and refining surgical ablative and reconstructive approaches to facilitate functional restoration of patients without compromising survival. We now have a much clearer understanding of the disease, its management and the rehabilitation of patients. But there is still much to be done. This book aims to cover a range of exciting new findings in clinical sciences, basic sciences and allied specialties with an emphasis on their relevance to HNC. This work promises to improve preventive and therapeutic strategies and will hopefully culminate in improved outcomes of HNC. The contributions have been made by established leaders in the field and every effort has been made to address the issue in a comprehensive, yet concise, manner for the benefit of readers. We believe that this book will be of value to established/in-training clinicians, scientists, allied professionals, as well as medical students who have inquisitive minds and wish to further enhance their knowledge of HNC.
Author: Hellen Gelband,Prabhat Jha,Rengaswamy Sankaranarayanan,Susan Horton
Publisher: World Bank Publications
Volume 3, Cancer, presents the complex patterns of cancer incidence and death around the world and evidence on effective and cost-effective ways to control cancers. The DCP3 evaluation of cancer will indicate where cancer treatment is ineffective and wasteful, and offer alternative cancer care packages that are cost-effective and suited to low-resource settings. Main messages from the volume include: -Quality matters in all aspects of cancer treatment and palliation. -Cancer registries that track incidence, mortality, and survival †“ paired with systems to capture causes of death are important to understanding the national cancer burden and the effect of interventions over time. -Effective interventions exist at a range of prices. Adopting "resource appropriate" measures which allow the most effective treatment for the greatest number of people will be advantageous to countries. -Prioritizing resources toward early stage and curable cancers is likely to have the greatest health impact in low income settings. -Research prioritization is no longer just a global responsibility. Providing cancer treatment requires adequate numbers of trained healthcare professionals and infrastructure beyond what is available in most LMICs, especially low income countries. Careful patient monitoring is a requirement of good quality cancer care and this often involves laboratory tests in addition to clinical examination. Even if financing were immediately available to build or expand a cancer control system, reaching capacity will take many years.
Author: Waun Ki Hong,William N. Hait
The consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists and others who treat cancer patients, Cancer Medicine 8 covers the ever-widening sphere of current cancer knowledge and clinical practice. In this new 8th edition an outstanding editorial team from world-renowned medical centers continues to hone the leading edge forged in previous editions, with timely information on biology, immunology, etiology, epidemiology, prevention, screening, pathology, imaging and therapy. The book is a testament to the editorial panel's creed that innovative, comprehensive, multidisciplinary treatment of cancer patients must be grounded in a fundamental understanding of cancer biology. Cancer Medicine 8 does a superb job of bringing scientific principles into clinical practice. This text is the ultimate resource of new information providing the basis for better informed cancer therapy choices. Cancer Medicine 8 features hundreds of 4-color illustrations, photographs, tables, graphs and algorithms that make this text an invaluable clinical tool in recognizing characteristic appearances of both patient and tissue. The 137 tightly focused chapters are organized into 5 sections: I: Cardinal Manifestations of Cancer II: Scientific Foundations of Cancer III: Principles of Cancer Diagnosis IV: Principles of Therapeutic Modalities V: Principles of Multidisciplinary Management Major Revisions: Chapter 6: Oncogenes An entire section is devoted to oncogenes like kit, Ret, Braf, Akt genes and the new drugs that specifically target them. This chapter not only provides a list of these new therapies but also insight as to how they target the oncogenes and their mutations, as well as therapy response and efficacy. Chapter 11: Tumor Angiogenesis This chapter provides a wealth of new data and understanding of the mechanisms of angiogenesis and how it contributes to the malignancy of various cancers The Clinical Advancement section provides an extensive summary of new trials investigating numerous novel angiogenesis agents Chapter 33: Chemoprevention This chapter also provides a considerable amount of new information for a broad range of clinical trials such as the HPV vaccine trial Future, Select, Star, Approve and PreSAP. The rationales for these trials are discussed and resulting data from the completed trials are presented. Chapter 55: Cytokines Research on cytokines is another area that is exploding in magnitude. This chapter presents a wealth of new information on promising new therapeutic agents.There is also updated information on the therapeutic usage of currently available agents such as hemotopoietic growth factors (HGF), erythropoietin and thromobopoietic agents. Chapter 56: Monoclonal Serotherapy A considerable amount of research has been done in the past few years on therapeutic and targeted agents in cancer therapy. Updated information and data is provided from recent trials for therapies previously discussed in Cancer Medicine edition 7 covering therapeutic agents and targeted toxins. Chapter 77: Neoplasms of the Head and Neck There is a discussion of changes in treatment methods for certain cancers such as the recent shift from surgery to combined chemotherapy with radiotherapy for tonsillar cancer, nasal and paranasal sinuses cancers and laryngeal cancer. Chapter 78: Lung Cancer Advances in diagnostic techniques are described such as ultrasound-guided fine needle aspiration or electromagnetic navigation diagnostic bronchoscopy. Video assisted thoracoscopic surgery (VATS) discussion is updated. New sections are devoted to prognostic and predictive biomarkers.
Author: World Health Organization
Publisher: World Health Organization
Category: Health & Fitness
This manual encourages countries to conduct standardized oral health surveys that are comparable internationally. The manual provides guidelines for assessing the current oral health status of a population and the future needs for oral health intervention. Oral diseases are among the most prevalent non-communicable diseases and major components of the global burden of disease. The key risk factors are common to chronic and oral diseases. Guidelines are presented for risk factors assessment. The WHO approach can facilitate the incorporation of oral health into national health surveillance systems. Surveillance of oral health over time and monitoring of programs may provide decision-makers, public health planners, and health administrators with valuable information about the relevance and cost-effectiveness of public health intervention programs.
Concepts, Principles and Controversies
Author: Rosalind A. Eeles,Christine D. Berg,Jeffrey S. Tobias
Publisher: John Wiley & Sons
Cancer Prevention and Screening offers physicians and all clinical healthcare professionals a comprehensive, useful source of the latest information on cancer screening and prevention with both a global and a multidisciplinary perspective. Includes background information on epidemiology, cancer prevention, and cancer screening, for quick reference Offers the latest information for clinical application of the most recent techniques in prevention and screening of all major and many lesser cancer types Emphasises the importance of multidisciplinary teamwork in cancer screening Highlights frequent dilemmas and difficulties encountered during cancer screening Provides clear-cut clinical strategies for optimal patient education, communication, and compliance with cancer prevention techniques
Author: KMK Masthan,Vidyarani Shyamsundar,N Aravindha Babu
Publisher: JP Medical Ltd
Oral cancer can affect any part of the mouth, including the tongue and lips. Symptoms include a sore or ulcer for more than three weeks. Accurate and rapid diagnosis can help in extending survival and preventing the progression of disease. Color Atlas of Oral cancer covers all aspects of oral cancer, serving as a straightforward guide and reference for dentists and clinicians. This book provides an overview of clinical examination and a complete list of recent advances in radiographic diagnostic aids. Treatment options and prevention are also covered in depth. Atlas of Oral Cancer features nearly 200 images including histopathology photographs. Key Points Full colour photographic details of histopathology of potentially malignant disorders and squamous cell carcinoma Aids understanding of oral cancer and the importance of preventive measures Details a variety of oral cancers from causes and presentation, through to screening, diagnosis, treatment and prevention Includes nearly 200 images
Author: U. S. Preventive Services Task Force
Publisher: DIANE Publishing
A report on recommended clinical preventive services that should be provided to patients in the course of routine clinical care, including screening for vascular, neoplastic and infectious diseases, and metabolic, hematologic, ophthalmologic and ontologic, prenatal, and musculoskeletal disorders. Also, mental disorders and substance abuse, counseling, and immunizations/chemoprophylaxis. Tables.
The Surprising Link between Your Teeth, Real Food, and Life-Changing Natural Health
Author: Steven Lin
Publisher: Hay House, Inc
Category: Health & Fitness
Throughout the years, dental health has often been characterized as a reflection of our overall health, where bad oral health results from issues with other parts of our body. But what if we flipped the paradigm? What if we thought about dental health as the foundation for our physical health as a whole? Dr. Steven Lin, an experienced dentist and the world’s first dental nutritionist, has analyzed our ancestral traditions, epigenetics, gut health, and the microbiome in order to develop food-based principles for a literal top-down holistic health approach. Merging dental and nutritional science, Dr. Lin lays out the dietary program that can help ensure you won’t need dental fillings or cholesterol medications —and give you the resources to raise kids who develop naturally straight teeth. With our mouth as the gatekeeper of our gut, keeping our oral microbiome balanced will create a healthy body through a healthy mouth. Dr. Lin arms you with a 40-day meal plan, complete with the Dental Diet food pyramid, exercises for the mouth, recipes, and cooking techniques to help you easily and successfully implement his techniques into your everyday life. The tools to improve overall wellness levels and reverse disease are closer than we think —in our markets, in our pantries, and, most frequently, in our mouths —if not just a well-chosen bite or two away.
Author: Institute of Medicine,Division of Health Care Services,Committee on Medicare Coverage Extensions
Publisher: National Academies Press
This report, which was developed by an expert committee of the Institute of Medicine, reviews the first three services listed above. It is intended to assist policymakers by providing syntheses of the best evidence available about the effectiveness of these services and by estimating the cost to Medicare of covering them. For each service or condition examined, the committee commissioned a review of the scientific literature that was presented and discussed at a public workshop. As requested by Congress, this report includes explicit estimates only of costs to Medicare, not costs to beneficiaries, their families, or others. It also does not include cost-effectiveness analyses. That is, the extent of the benefits relative to the costs to Medicare-or to society generally-is not evaluated for the services examined. The method for estimating Medicare costs follows the generic estimation practices of the Congressional Budget Office (CBO). The objective was to provide Congress with estimates that were based on familiar procedures and could be compared readily with earlier and later CBO estimates. For each condition or service, the estimates are intended to suggest the order of magnitude of the costs to Medicare of extending coverage, but the estimates could be considerably higher or lower than what Medicare might actually spend were coverage policies changed. The estimates cover the five-year period 2000-2004. In addition to the conclusions about specific coverage issues, the report examines some broader concerns about the processes for making coverage decisions and about the research and organizational infrastructure for these decisions. It also briefly examines the limits of coverage as a means of improving health services and outcomes and the limits of evidence as a means of resolving policy and ethical questions.
Author: Charles F. Streckfus
This book reviews the progress made in salivary diagnostics during the past two decades and identifies the likely direction of future endeavors. After an introductory section describing the histological and anatomical features of the salivary glands and salivary function, salivary collection devices and diagnostic platforms are reviewed. The field of “salivaomics” is then considered in detail, covering, for example, proteomics, the peptidome, DNA and RNA analysis, biomarkers, and methods for biomarker discovery. Salivary diagnostics for oral and systemic diseases are thoroughly discussed, and the role of salivary gland tissue engineering for future diagnostics is explored. The book closes by considering legal issues and barriers to salivary diagnostic development. Advances in Salivary Diagnostics will be an informative and stimulating reference for both practitioners and students.
Author: Anthony B. Miller
Publisher: Kluwer Academic Pub
Screening for cancer is an important focus of cancer control. Yet screening, as it involves administering a test to large segments of the population deemed to be at risk for the disease of interest, is potentially a major consumer of scarce health care resources. In addition, the benefits sought from cancer screening, particularly reduction in mortality from the disease, are not always realized, either for biological or organizational reasons. Thus, the paradigm that 'early detection must always be beneficial', taught to health care professionals, and publicized widely through the media to the public, has been challenged in the last two decades for a number of cancer sites. It is the purpose of Advances in Cancer Screening to determine the extent to which the requirements for the introduction of population-based screening programs have been met, as a result of extensive research on screening during the last two decades, with a major concentration on findings from the recent decade.
Author: Mary-Ann Mycek,Brian W. Pogue
Publisher: CRC Press
Melding basic and clinical science, this reference provides a comprehensive overview of the roles that biophysics, photochemistry, and computational modeling play in the biomedical applications of fluorescence spectroscopy and imaging. Penned by pioneering researchers, the Handbook of Biomedical Fluorescence discusses fundamental aspects of fluorescence generation in organic molecules within tissue, theoretical and experimental views of how light propagation in tissue can be used to interpret fluorescence signals, endogenous and exogenous fluorescence agents in medical or basic research studies, and radiation transport, diffusion theory, and the Monte Carlo method.
Author: World Health Organization,International Agency for Research on Cancer
Publisher: World Health Organization
This eighty-ninth volume of the IARC Monographs is the third and last of a series on tobacco-related agents. Volume 83 (ISBN 9789283212836) reported on the carcinogenicity of tobacco smoke and involuntary smoking (second-hand smoke or environmental tobacco smoke) (IARC, 2004a). Volume 85 (ISBN 9789283212850) summarized the evidence on the carcinogenic risk of chewing betel quid with and without tobacco (IARC, 2004b). That volume explored the variety of products chewed in South Asia and other parts of the word that contain areca nut in combination with other ingredients, often including tobacco. In this eighty-ninth volume, the carcinogenic risks associated with the use of smokeless tobacco, including chewing tobacco and snuff, are considered in a first monograph. The second monograph reviews some tobacco-specific nitrosamines. These agents were evaluated earlier in Volume 37 of the Monographs (IARC, 1985, ISBN 9789283215370), and information gathered since that time has been summarised and evaluated.
7 Steps in 7 Days to Lose Weight, Fight Inflammation, and Reclaim Your Health and Energy
Author: Daryl Gioffre
Publisher: Da Capo Lifelong Books
Category: Health & Fitness
Easy, customizable plans (2-day, 7-day, and longer) to rid your diet of the acidic foods (sugar, dairy, gluten, excess animal proteins, processed foods) that cause inflammation and wreak havoc on your health. Let's talk about the four-letter word that's secretly destroying your health: ACID. An acidic lifestyle--consuming foods such as sugar, grains, dairy, excess animal proteins, processed food, artificial sweeteners, along with lack of exercise and proper hydration, and stress--causes inflammation. And inflammation is the culprit behind many of our current ailments, from weight gain to chronic disease. But there's good news: health visionary Dr. Daryl Gioffre shares his revolutionary plan to rid your diet of highly acidic foods, alkalize your body and balance your pH. With the Get Off Your Acid plan, you'll: Gain more energy Strengthen your immune system Diminish pain and reflux Improve digestion, focus, and sleep Lose excess weight and bloating, naturally With alkaline recipes for easy, delicious snacks and meals, Get Off Your Acid is a powerful guide to transform your health and energy--in seven days.
A Global Perspective
Publisher: Amer Inst for Cancer Research
Category: Health & Fitness
The Second Expert Report, Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective offers the most up-to-date recommendations for individuals and populations. They are based on the conclusions of an expert panel that certain foods, drinks and lifestyle choices protect against or lead to the development of one or more types of cancer. Additionally, the report explains how the panel reached its conclusions and what those conclusions mean to researchers, educators, practitioners and policymakers around the world. It is the largest report of its kind ever done, covering 60 exposures in relationship to 17 cancer sites. 7,000 individual studies were consulted. Book includes a CD containing the most complete bibliography and presentation of the data ever compiled.
Author: R. Sankaranarayanan,J. Wahrendorf,E. Démaret
Publisher: Oxford University Press, USA
This directory is an annual compendium of current research in epidemiology. The 1994 edition (17th in the series) contains abstracts of the 1246 projects being carried out in over 80 countries, and reflects the huge range of epidemiological research into the distribution, causes, and prevention of cancer around the world. Each project is indexed in up to eight separate indexes, enabling rapid searches for current studies fitting almost any description. The eight indexes are: name of investigator(s); keywords; cancer site(s); study type (cohort, case-control, etc.); country; chemical exposure; occupational exposure; and cancer registry. The Directory also includes comprehensive lists of 261 population-based cancer registries and over 300 biological material banks, all available for collaboration in epidemiological research. The addresses, telephone and telex numbers of nearly 1000 principal investigators is provided to improve contact between research workers.
The FlowingData Guide to Design, Visualization, and Statistics
Author: Nathan Yau
Publisher: John Wiley & Sons
How Innovative Colleges Drive Student Success
Author: Gloria Cordes Larson
Publisher: John Wiley & Sons
How can we as parents, educators, and members of the business community prepare students to be successful leaders in today's global environment? It's a critically important question. Gloria Cordes Larson, president of Bentley University, explains why today's practices in higher education are inadequate preparation for our rapidly evolving innovation economy. Instead, she passionately advocates for a hybrid-learning model that integrates business education with traditional liberal arts courses. Today's businesses demand a new kind of hybrid graduate, possessed of both hard and soft skills, with the courage to take risks, the creativity to innovate, and the savvy to excel in a turbulent competitive climate. This book is a valuable resource for participants in every learning community: our homes, schools, and businesses. It will change the way you think about what excellence in education means in today's business environment as you develop strategies that will move our children, students, and future employees forward in a rapidly changing and very challenging world. Prepared with that training and knowledge, they will find greater fulfillment and make their own mark on the future.
Author: Anthony William
Publisher: Hay House, Inc
Category: Body, Mind & Spirit
Anthony William, the one and only Medical Medium, has helped tens of thousands of people heal from ailments that have been misdiagnosed or ineffectively treated or that doctors can’t resolve. He’s done this by listening to a divine voice that literally speaks into his ear, telling him what lies at the root of people’s pain or illness and what they need to do to restore their health. His methods achieve spectacular results, even for those who have spent years and many thousands of dollars on all forms of medicine before turning to him. Now, in this revolutionary book, he opens the door to all he has learned in over 25 years of bringing people’s lives back: a massive amount of healing information, much of which science won’t discover for decades, and most of which has never appeared anywhere before. Medical Medium reveals the root causes of diseases and conditions that medical communities either misunderstand or struggle to understand at all. It explores all-natural solutions for dozens of the illnesses that plague us, including Lyme disease, fibromyalgia, adrenal fatigue, chronic fatigue syndrome, hormonal imbalances, Hashimoto’s disease, multiple sclerosis, depression, neurological conditions, chronic inflammation, autoimmune disease, blood sugar imbalances, colitis and other digestive disorders, and more. It also offers solutions for restoring the soul and spirit after illness has torn at our emotional fabric. Whether you’ve been given a diagnosis you don’t understand, or you have symptoms you don’t know how to name, or someone you love is sick, or you want to care for your own patients better, Medical Medium offers the answers you need. It’s also a guidebook for everyone seeking the secrets to living longer, healthier lives. "The truth about the world, ourselves, life, purpose—it all comes down to healing," Anthony William writes. "And the truth about healing is now in your hands."