Author: Anne E. McDermott,Tatyana Polenova

Publisher: John Wiley & Sons

ISBN: 1118588886

Category: Science

Page: 592

View: 4671

The content of this volume has been added to eMagRes (formerly Encyclopedia of Magnetic Resonance) - the ultimate online resource for NMR and MRI. The field of solid state NMR of biological samples [ssNMR] has blossomed in the past 5-10 years, and a cohesive overview of the technology is needed for new practitioners in industry and academia. This title provides an overview of Solid State NMR methods for studying structure dynamics and ligand-binding in biopolymers, and offers an overview of RF pulse sequences for various applications, including not only a systematic catalog but also a discussion of theoretical tools for analysis of pulse sequences. Practical examples of biochemical applications are included, along with a detailed discussion of the many aspects of sample preparation and handling that make spectroscopy on solid proteins successful. About EMR Handbooks / eMagRes Handbooks The Encyclopedia of Magnetic Resonance (up to 2012) and eMagRes (from 2013 onward) publish a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of EMR Handbooks / eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of articles from eMagRes. In consultation with the eMagRes Editorial Board, the EMR Handbooks / eMagRes Handbooks are coherently planned in advance by specially-selected Editors, and new articles are written (together with updates of some already existing articles) to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this Handbook and the complete content of eMagRes at your fingertips! Visit: www.wileyonlinelibrary.com/ref/eMagRes View other eMagRes publications here
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MRS Theory, Practice and Applications

Author: Paul A. Bottomley,John R. Griffiths

Publisher: John Wiley & Sons

ISBN: 1118997670

Category: Medical

Page: 1232

View: 1244

This handbook covers the entire field of magnetic resonance spectroscopy (MRS), a unique method that allows the non-invasive identification, quantification and spatial mapping of metabolites in living organisms–including animal models and patients. Comprised of three parts: Methodology covers basic MRS theory, methodology for acquiring, quantifying spectra, and spatially localizing spectra, and equipment essentials, as well as vital ancillary issues such as motion suppression and physiological monitoring. Applications focuses on MRS applications, both in animal models of disease and in human studies of normal physiology and disease, including cancer, neurological disease, cardiac and muscle metabolism, and obesity. Reference includes useful appendices and look up tables of relative MRS signal-to-noise ratios, typical tissue concentrations, structures of common metabolites, and useful formulae. About eMagRes Handbooks eMagRes (formerly the Encyclopedia of Magnetic Resonance) publishes a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of eMagRes articles. In consultation with the eMagRes Editorial Board, the eMagRes Handbooks are coherently planned in advance by specially-selected Editors, and new articles are written to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this handbook and the complete content of eMagRes at your fingertips! Visit the eMagRes Homepage
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Fundamentals and Methods

Author: Daniella Goldfarb,Stefan Stoll

Publisher: John Wiley & Sons

ISBN: 111916298X

Category: Science

Page: 648

View: 9418

This unique, self-contained resource is the first volume on electron paramagnetic resonance (EPR) spectroscopy in the eMagRes Handbook series. The 27 chapters cover the theoretical principles, the common experimental techniques, and many important application areas of modern EPR spectroscopy. EPR Spectroscopy: Fundamentals and Methods is presented in four major parts: A: Fundamental Theory, B: Basic Techniques and Instrumentation, C: High-Resolution Pulse Techniques, and D: Special Techniques. The first part of the book gives the reader an introduction to basic continuous-wave (CW) EPR and an overview of the different magnetic interactions that can be determined by EPR spectroscopy, their associated theoretical description, and their information content. The second provides the basics of the various EPR techniques, including pulse EPR, and EPR imaging, along with the associated instrumentation. Parts C and D builds on parts A and B and offer introductory accounts of a wide range of modern advanced EPR techniques, with examples of applications. The last two parts presents most of the new advances that do not appear in most of the classical EPR textbooks that focus on CW EPR. EPR Spectroscopy: Fundamentals and Methods contains, in concise form, all the material needed to understand state-of-the-art EPR spectroscopy at the graduate school/research level, whilst the editors have ensured that it presents the topic at a level accessible to newcomers to the field and others who want to know its range of application and how to apply it.
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Author: Maria Cristina Tanzi,Silvia Farè

Publisher: Woodhead Publishing

ISBN: 0081007434

Category: Technology & Engineering

Page: 500

View: 6332

Characterization of Polymeric Biomaterials presents a comprehensive introduction on the topic before discussing the morphology and surface characterization of biomedical polymers. The structural, mechanical, and biological characterization is described in detail, followed by invaluable case studies of polymer biomaterial implants. With comprehensive coverage of both theoretical and experimental information, this title will provide scientists with an essential guide on the topic of these materials which are regularly used for clinical applications, such as implants and drug delivery devices. However, a range of novel polymers and the development and modification of existing medical polymers means that there is an ongoing need to satisfy particular design requirements. This book explains the critical and fundamentals methods to characterize polymer materials for biomedical applications. Presents a self-contained reference on the characterization of polymeric biomaterials Provides comprehensive information on how to characterize biomedical polymers in order to improve design and synthesis Includes useful case studies that demonstrate the characterization of biomaterial implants
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Author: Khouloud Jlassi,Mohamed M. Chehimi,Sabu Thomas

Publisher: Elsevier

ISBN: 0323461611

Category: Technology & Engineering

Page: 546

View: 3508

Clay–Polymer Nanocomposites is a complete summary of the existing knowledge on this topic, from the basic concepts of synthesis and design to their applications in timely topics such as high-performance composites, environment, and energy issues. This book covers many aspects of synthesis such as in- situ polymerization within the interlamellar spacing of the clays or by reaction of pristine or pre-modified clays with reactive polymers and prepolymers. Indeed, nanocomposites can be prepared at industrial scale by melt mixing. Regardless the synthesis method, much is said in this book about the importance of theclay pre-modification step, which is demonstrated to be effective, on many occasions, in obtaining exfoliated nanocomposites. Clay–Polymer Nanocomposites reports the background to numerous characterization methods including solid state NMR, neutron scattering, diffraction and vibrational techniques as well as surface analytical methods, namely XPS, inverse gas chromatography and nitrogen adsorption to probe surface composition, wetting and textural/structural properties. Although not described in dedicated chapters, numerous X-ray diffraction patterns of clay–polymer nanocomposites and reference materials are displayed to account for the effects of intercalation and exfoliations of layered aluminosilicates. Finally, multiscale molecular simulation protocols are presenting for predicting morphologies and properties of nanostructured polymer systems with industrial relevance. As far as applications are concerned, Clay–Polymer Nanocomposites examines structural composites such as clay–epoxy and clay–biopolymers, the use of clay–polymer nanocomposites as reactive nanocomposite fillers, catalytic clay-(conductive) polymers and similar nanocomposites for the uptake of hazardous compounds or for controlled drug release, antibacterial applications, energy storage, and more. The most comprehensive coverage of the state of the art in clay–polymer nanocomposites, from synthesis and design to opportunities and applications Covers the various methods of characterization of clay–polymer nanocomposites - including spectroscopy, thermal analyses, and X-ray diffraction Includes a discussion of a range of application areas, including biomedicine, energy storage, biofouling resistance, and more
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Measurements and Empirical Models

Author: J. Barrie Billingsley

Publisher: IET

ISBN: 9780852962305

Category: TECHNOLOGY & ENGINEERING

Page: 703

View: 4081

In this unique book, Billingsley solves the problem of radar land clutter by showing the reader how to design and predict the performance of radars that operate in situations where echoes from the earth's surface interfere with radar target echoes.
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Author: Bernhard Blümich,Sabina Haber-Pohlmeier,Wasif Zia

Publisher: Walter de Gruyter GmbH & Co KG

ISBN: 3110374587

Category: Technology & Engineering

Page: 289

View: 5058

Nuclear Magnetic Resonance (NMR) spectroscopy is the most popular method for chemists to analyze molecular structures while Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic tool for medical doctors that provides high-contrast images of biological tissue depicting the brain function and the beating heart. The book offers a basic introduction to NMR with portable devices, the equipment, the experimental set-up, types of NMR experiments, example applications, and data evaluation procedures. Each description follows the same didactic pattern: introduction, basic theory, pulse sequences and parameters, beginners-level measurements, advanced-level measurements, data processing. Mobile NMR simplified to approach the level of operating a smart phone!
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Author: Richard M. Epand

Publisher: CRC Press

ISBN: 9780849349263

Category: Medical

Page: 416

View: 3376

The Amphipathic Helix is a comprehensive volume discussing amphipathic helices in systems as diverse as serum lipoproteins, lung surfactant, cytotoxic peptides, ion channels, mitochondrial targeting, peptide hormones, G proteins, T-cell recognition, DNA binding proteins, and antifreeze proteins. The book also includes general introductory material that defines amphipathic helices, discusses methods to identify amphipathic helical segments from the amino acid sequence of a protein, illustrates how amphipathic helices can be used in the de novo design of peptide and protein structures, and describes how these helices stabilize protein structures. There is also a section on techniques to determine helix orientation in a membrane environment using polarized attenuated total reflection infrared spectroscopy or solid state NMR spectroscopy. Recent developments on all these topics have been discussed by leading experts in this reference for researchers and students in biochemistry, biophysics, and pharmacology.
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Author: Devashish Shrivastava

Publisher: John Wiley & Sons

ISBN: 1119127327

Category: Science

Page: 904

View: 6080

An authoritative guide to theory and applications of heat transfer in humans Theory and Applications of Heat Transfer in Humans 2V Set offers a reference to the field of heating and cooling of tissue, and associated damage. The author—a noted expert in the field—presents, in this book, the fundamental physics and physiology related to the field, along with some of the recent applications, all in one place, in such a way as to enable and enrich both beginner and advanced readers. The book provides a basic framework that can be used to obtain ‘decent’ estimates of tissue temperatures for various applications involving tissue heating and/or cooling, and also presents ways to further develop more complex methods, if needed, to obtain more accurate results. The book is arranged in three sections: The first section, named ‘Physics’, presents fundamental mathematical frameworks that can be used as is or combined together forming more complex tools to determine tissue temperatures; the second section, named ‘Physiology’, presents ideas and data that provide the basis for the physiological assumptions needed to develop successful mathematical tools; and finally, the third section, named ‘Applications’, presents examples of how the marriage of the first two sections are used to solve problems of today and tomorrow. This important text is the vital resource that: Offers a reference book in the field of heating and cooling of tissue, and associated damage. Provides a comprehensive theoretical and experimental basis with biomedical applications Shows how to develop and implement both, simple and complex mathematical models to predict tissue temperatures Includes simple examples and results so readers can use those results directly or adapt them for their applications Designed for students, engineers, and other professionals, a comprehensive text to the field of heating and cooling of tissue that includes proven theories with applications. The author reveals how to develop simple and complex mathematical models, to predict tissue heating and/or cooling, and associated damage.
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Nanocarriers

Author: Nina Dragicevic,Howard I. Maibach

Publisher: Springer

ISBN: 3662478625

Category: Medical

Page: 384

View: 8083

Percutaneous Penetration Enhancers in a mini-series format comprising five volumes, represents the most comprehensive reference on enhancement methods – both well established and recently introduced – in the field of dermal/transdermal drug delivery. In detail the broad range of both chemical and physical methods used to enhance the skin delivery of drugs is described. All aspects of drug delivery and measurement of penetration are covered and the latest findings are provided on skin structure and function, mathematics in skin permeation and modern analytical techniques adapted to assess and measure penetration. In offering a detailed description of the methods currently in use for penetration enhancement, this book will be of value for researchers, pharmaceutical scientists, practitioners and also students.​
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Author: Warren S. Warren

Publisher: Academic Press

ISBN: 1483281450

Category: Science

Page: 286

View: 6242

Advances in Magnetic and Optical Resonance contains three articles which review quite fundamentally different aspects of coherent spectroscopy. An enormous variety of effects can be observed when optical and spin resonances are coupled, usually by a combination of radio frequency and laser irradiation. The first article reviews these effects and pays particular attention to developing a theoretical framework which is as similar as possible for the optical and spin cases. Subsequent articles examine deuterium relaxation in molecular solids, and the spatiotemporal growth of multiple spin coherences in networks of strongly dipolar coupled spins driven by radiofrequency fields.
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Fundamentals

Author: Shri Singh,David A. Dunmur

Publisher: World Scientific

ISBN: 9789810242503

Category: Science

Page: 531

View: 9346

Liquid crystals are partially ordered systems without a rigid, long-range structure. The study of these materials covers a wide area: chemical structure, physical properties and technical applications. Due to their dual nature -- anisotropic physical properties of solids and rheological behavior of liquids -- and easy response to externally applied electric, magnetic, optical and surface fields liquid crystals are of greatest potential for scientific and technological applications. The subject has come of age and has achieved the status of being a very exciting interdisciplinary field of scientific and industrial research. This book is an outgrowth of the enormous advances made during the last three decades in both our understanding of liquid crystals and our ability to use them in applications. It presents a systematic, self-contained and up-to-date overview of the structure and properties of liquid crystals. It will be of great value to graduates and research workers in condensed matter physics, chemical physics, biology, materials science, chemical and electrical engineering, and technology from a materials science and physics viewpoint of liquid crystals.
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Author: Julie Fisher

Publisher: CRC Press

ISBN: 1466592249

Category: Science

Page: 363

View: 5280

A blend of theory and practical advice, Modern NMR Techniques for Synthetic Chemistry illustrates how NMR spectroscopy can be used to determine the abundance, size, shape, and function of organic molecules. It provides you with a description the NMR technique used (more pictorial than mathematical), indicating the most common pulse sequences, some practical information as appropriate, followed by illustrative examples. This format is followed for each chapter so you can skip the more theoretical details if the practical aspects are what interest you. Following a discussion of basic parameters, the book describes the utility of NMR in detecting and quantifying dynamic processes, with particular emphasis on the usefulness of saturation-transfer (STD) techniques. It details pulsed–field gradient approaches to diffusion measurement, diffusion models, and approaches to ‘inorganic’ nuclei detection, important as many synthetic pathways to new organics involve heavier elements. The text concludes with coverage of applications of NMR to the analysis of complex mixtures, natural products, carbohydrates, and nucleic acids—all areas of activity for researchers working at the chemistry-life sciences interface. The book’s unique format provides some theoretical insight into the NMR technique used, indicating the most common pulse sequences. The book draws upon several NMR methods that are resurging or currently hot in the field and indicates the specific pulse sequence used by various spectrometer manufacturers for each technique. It examines the analysis of complex mixtures, a feature not found in most books on this topic.
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Author: Kenneth J.D. MacKenzie,M.E. Smith

Publisher: Elsevier

ISBN: 9780080537108

Category: Science

Page: 748

View: 5617

Techniques of solid state nuclear magnetic resonance (NMR) spectroscopy are constantly being extended to a more diverse range of materials, pressing into service an ever-expanding range of nuclides including some previously considered too intractable to provide usable results. At the same time, new developments in both hardware and software are being introduced and refined. This book covers the most important of these new developments. With sections addressed to non-specialist researchers (providing accessible answers to the most common questions about the theory and practice of NMR asked by novices) as well as a more specialised and up-to-date treatment of the most important areas of inorganic materials research to which NMR has application, this book should be useful to NMR users whatever their level of expertise and whatever inorganic materials they wish to study.
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Author: Daniel J. MacPhee

Publisher: Springer

ISBN: 3319514091

Category: Science

Page: 155

View: 4153

Due to the paucity of reviews on this subject, this volume aims to be timely and promote additional basic and translational research on these proteins in reproductive system development and function within the fields of Anatomy, Embryology and Cell Biology. The breadth of the work being conducted within Reproduction is exemplified by the contributors to this series who will provide reviews on: Grp78 roles in female reproduction, small heat shock proteins/co-chaperones as players in uterine smooth muscle function, the role of heat shock proteins in sperm function and maternal contribution to oogenesis and early embryogenesis, heat shock factors and testes development, HSP90 in ovarian biology and pathology, and the role of HSP70 in regulation of autophagy in pregnancy and parturition.
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Science and Practice

Author: Simon Shackley,Greet Ruysschaert,Kor Zwart,Bruno Glaser

Publisher: Routledge

ISBN: 1134654871

Category: Technology & Engineering

Page: 302

View: 5225

This user-friendly book introduces biochar to potential users in the professional sphere. It de-mystifies the scientific, engineering and managerial issues surrounding biochar for the benefit of audiences including policy makers, landowners and farmers, land use, agricultural and environmental managers and consultants, industry and lobby groups and NGOs. The book reviews state-of-the-art knowledge in an approachable way for the non-scientist, covering all aspects of biochar production, soil science, agriculture, environmental impacts, economics, law and regulation and climate change policy. Chapters provide ‘hands-on’ practical information, including how to evaluate biochar and understand what it is doing when added to the soil, how to combine biochar with other soil amendments (such as manure and composts) to achieve desired outcomes, and how to ensure safe and effective use. The authors also present research findings from the first coordinated European biochar field trial and summarize European field trial data. Explanatory boxes, infographics and concise summaries of key concepts are included throughout to make the subject more understandable and approachable.
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Author: Frank A. Bovey,Peter A. Mirau

Publisher: Academic Press

ISBN: 9780080537580

Category: Technology & Engineering

Page: 459

View: 5101

NMR has made important contributions to our understanding of structure–property relationships in polymers. This book provides an up-to-date and comprehensive overview of the fundamentals of NMR, with applications of multidimensional NMR and the new solution and solid-state methods in polymer science. NMR of Polymers is written by leading authorities for graduate students and professionals in academia and industry. Provides comprehensive overview of NMR in Polymer Science Covers multidimensional NMR Includes new solution and solid state methods Addresses chain conformation and dynamics
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Advanced Methods, Properties And Applications

Author: E A Ghabbour,G. Davies

Publisher: Woodhead Publishing

ISBN: 1782424385

Category: Science

Page: 302

View: 5927

Reporting on front-line research into these natural materials, this volume focuses on the use of chemical and physical methodology in seeking an explanation of the structures of humic substances (HSs) and their relation to their microscopic properties.
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Author: Lech Wojciech Szajdak

Publisher: Springer

ISBN: 3319431072

Category: Technology & Engineering

Page: 312

View: 404

This volume looks at the impact that different cropping systems and tillage have on soil’s biologically active substances. It considers how phytotoxins accumulate and can inhibit the development of cultivated plants. Coverage explores the continuous cropping of rye, crop rotation, no tillage, and conventional tillage. It offers a comprehensive, comparative approach to allelopathic plant-soil interactions. The authors focus on free and bounded biologically active substances such as amino acids, auxins, humic and fulvic acids, transient radicals, and enzymes in light sand soils fertilized with different mineral and organic fertilizers. The chapters address fundamental questions relevant to the environmental challenges we face today and will deal with in the future. The results involve asking basic questions motivated by soil's chemical and biochemical processes. The answers will lead to the improvement of the quality of soil’s organic matter, which, in turn, can lead to increased crop yields. Readers will come to understand the relationship between ecological processes and environmental change on individual levels of biocomplexity as well as on systems in their entirety. The title is ideal for students and teachers for laboratory practical classes. Soil scientists, biochemists, chemists, plant ecophysiologists, “Natural Products” organic chemists, and other environmental scientists and specialists will also find it useful.
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Author: N.A

Publisher: Academic Press

ISBN: 9780080585154

Category: Science

Page: 568

View: 2747

The major lipid components of biological membranes can undergo many diverse and fascinating morphological rearrangements. Studies of these diverse phases and the manner in which they are formed tends to alter the properties of ordinary bilayer membranes. This book examines the structural and biological roles of lipids forming non-lamellar structures. Key Features * Characterization of non-lamellar structures * Protein activity and membrane properties * Analysis of membrane fusion * Affect of non-lamellar forming lipids on biological systems
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