Author: David S. Goodsell

Publisher: Springer Science & Business Media

ISBN: 1475722672

Category: Science

Page: 140

View: 1037

A journey into the sub-microscopic world of molecular machines. Readers are first introduced to the types of molecules built by cells: proteins, nucleic acids, lipids, and polysaccharides. Then, in a series of distinctive illustrations, the reader is guided through the interior world of cells, exploring the ways in which molecules work in concert to perform the processes of living. Finally, the author shows us how vitamins, viruses, poisons, and drugs each have their effects on the molecules in our bodies. David Goodsell, author and illustrator, has prepared a fascinating introduction to biochemistry for the non-specialist. His book combines a lucid text with an abundance of drawings and computer graphics that present the world of cells and their components in a truly unique way.
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How Molecular Machines Extract Order from Chaos

Author: Peter Hoffmann,M Hoffmann

Publisher: Basic Books

ISBN: 0465033369

Category: Science

Page: 288

View: 1314

Below the calm, ordered exterior of a living organism lies microscopic chaos, or what the author calls the molecular storm--specialized molecules immersed in a whirlwind of colliding water molecules. Our cells are filled with molecular machines, which, like tiny ratchets, transform random motion into ordered activity, and create the "purpose" that is the hallmark of life. Tiny electrical motors turn electrical voltage into motion, nanoscale factories custom-build other molecular machines, and mechanical machines twist, untwist, separate and package strands of DNA. Life, the author argues, emerges from the random motions of atoms filtered through these sophisticated structures of our evolved machinery. The book is grounded in the author's own cutting-edge research.-Book Jacket.
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Author: Michal Kurzynski

Publisher: Springer Science & Business Media

ISBN: 3540336540

Category: Science

Page: 431

View: 3521

Thermodynamics was created in the ?rst half of the 19th century as a theory designed to explain the functioning of heat engines converting heat into mechanical work. In the course of time, while the scope of research in this ?eld was being extended to a wider and wider class of energy transformations, thermodynamics came to be considered as a general theory of machines identi?ed with energy transducers. Imp- tant progress in biochemistry in the ?rst half of the 20th century, and in molecular biology in the second half, made it possible to think of treating even living organisms as machines, at least on the subcellular level. However, success in applying thermodynamics to elucidate the phenomenon of life has been rather mitigated. Two reasons seem to be responsible for this unsatisfactory s- uation. Nineteenth century thermodynamics dealt only with simple (homogeneous) systems in complete equilibrium. Although during the 20th century a nonequilibrium thermodynamics was developed, sta- ing with the Onsager theory of linear response and ending with the Prigogine nonlinear theory of dissipative structures, these theories still concern the originally homogeneous systems. Because living organisms are complex systems with a historically frozen spatial and functional structure, a thermodynamics of both nonequilibrium and complex s- tems is needed for their description. The ?rst goal of the present book is to formulate the foundations of such a thermodynamics.
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Managing the Machinery of Your Life

Author: Sam Carpenter

Publisher: Greenleaf Book Group

ISBN: 1626342539

Category: Self-Help

Page: 192

View: 8860

Fix the machinery of your life . . . and serenity and wealth will follow. Starkly compelling in its simplicity, in The Systems Mindset: Managing the Machinery of Your Life, Sam Carpenter expands on the core inspirational element of his business bestseller, Work the System: The Simple Mechanics of Making More and Working Less, now in its third edition. Mindset is your path to quickly breaking free: to making a small tweak in how you see your world and then using that more accurate vision to get what you’ve always wanted from work, relationships, and health. When the systems mindset epiphany strikes, you will instantly see the visible and invisible machinery that determines your existence. With this startling new perception, you’ll see that your world is not a confusing array of sights, sounds, and events and, instead, grasp that it’s a simple and logical collection of systems, systems that can be quickly adjusted to deliver the life results you’ve always wanted. You will never be the same.
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Lessons from Nature

Author: David S. Goodsell

Publisher: John Wiley & Sons

ISBN: 0471469580

Category: Science

Page: 350

View: 480

Discussions of the basic structural, nanotechnology, and system engineering principles, as well as an introductory overview of essential concepts and methods in biotechnology, will be included. Text is presented side-by-side with extensive use of high-quality illustrations prepared using cutting edge computer graphics techniques. Includes numerous examples, such applications in genetic engineering. Represents the only available introduction and overview of this interdisciplinary field, merging the physical and biological sciences. Concludes with the authors' expert assessment of the future promise of nanotechnology, from molecular "tinkertoys" to nanomedicine. David Goodsell is author of two trade books, Machinery of Life and Our Molecular Nature, and Arthur Olson is the world's leader in molecular graphics and nano-scale representation.
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Seeing the Molecular Basis of Life

Author: David S. Goodsell

Publisher: Springer

ISBN: 3319325108

Category: Science

Page: 182

View: 4248

This book will take an evidence-based approach to current knowledge about biomolecules and their place in our lives, inviting readers to explore how we know what we know, and how current gaps in knowledge may influence the way we approach the information. Biomolecular science is increasingly important in our everyday life, influencing the choices we make about our diet, our health, and our wellness. Often, however, information about biomolecular science is presented as a list of immutable facts, discouraging critical thought. The book will introduce the basic tools of structural biology, supply real-life examples, and encourage critical thought about aspects of biology that are still not fully understood.
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Molecules, Organisms, and the Order of Life

Author: Franklin M. Harold

Publisher: Oxford University Press, USA

ISBN: 0195163389

Category: Science

Page: 305

View: 657

A leading microbiologist provides thought-provoking insights into the question of "What is Life?" as he examines the relationship of living things to the inorganic realms of physics and chemistry, explains how lifeless chemicals come together to form living beings, and details the true complexity of seemingly simple microorganisms such as E. coli.
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The Body’s Motors, Machines and Messages

Author: David S. Goodsell

Publisher: Springer Science & Business Media

ISBN: 1461223369

Category: Medical

Page: 183

View: 9099

Molecular Nature is a richly illustrated guide to the extraordinary diversity of molecules that are responsible for life. David Goodsell, author of the highly-praised book, The Machinery of Life, has synthesized a vast amount of data in a manner that is accessible to the general reader. Molecular Nature examines topics ranging from the shape of cells to the molecules responsible for digestion, immunity, and thought. The author's unique combination of scientific and artistic talents make this a readable, stimulating and highly evocative book. About the Author: David Goodsell is in the Department of Molecular Biology at the Research Institute of Scripps Clinic in La Jolla, California. His research involves computer graphics and X-ray crystallography. He is the author of The Machinery of Life (Springer-Verlag, 1992), and his artwork has been shown at exhibitions on science and art.
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A Computer in Every Living Cell

Author: Dennis Bray

Publisher: Yale University Press

ISBN: 0300155441

Category: Cell interaction

Page: 267

View: 8204

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Author: Paul R. Ehrlich

Publisher: Simon & Schuster

ISBN: N.A

Category: Science

Page: 320

View: 8035

This explanation of ecology, written specifically for nonscientists emphasizes the relationships of living things and their environment and the delicate balance of natural ecosystems
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Author: Ron Milo,Rob Phillips

Publisher: Garland Science

ISBN: 1317230698

Category: Science

Page: 400

View: 8874

Very little in our human experience is truly comparable to the immensely crowded and bustling interior of a cell. Biological numeracy provides a new kind of understanding of the cellular world. This book brings together up-to-date quantitative data from the vast biological literature and uses the powerful tool of "back of the envelope" estimates to reveal fresh perspectives and insights from numbers commonly encountered in cell biology. Readers gain a feeling for the sizes, concentrations, energies, and rates that characterize the lives of cellsÑ thereby shedding new light on the microscopic realm.
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A Visual Tour of the Building Block of Life

Author: Jack Challoner

Publisher: University of Chicago Press

ISBN: 022622421X

Category: Science

Page: 192

View: 1515

The cell is the basic building block of life. In its 3.5 billion years on the planet, it has proven to be a powerhouse, spreading life first throughout the seas, then across land, developing the rich and complex diversity of life that populates the planet today. With The Cell: A Visual Tour of the Building Block of Life, Jack Challoner treats readers to a visually stunning tour of these remarkable molecular machines. Most of the living things we’re familiar with—the plants in our gardens, the animals we eat—are composed of billions or trillions of cells. Most multicellular organisms consist of many different types of cells, each highly specialized to play a particular role—from building bones or producing the pigment in flower petals to fighting disease or sensing environmental cues. But the great majority of living things on our planet exist as single cell. These cellular singletons are every bit as successful and diverse as multicellular organisms, and our very existence relies on them. The book is an authoritative yet accessible account of what goes on inside every living cell—from building proteins and producing energy to making identical copies of themselves—and the importance of these chemical reactions both on the familiar everyday scale and on the global scale. Along the way, Challoner sheds light on many of the most intriguing questions guiding current scientific research: What special properties make stem cells so promising in the treatment of injury and disease? How and when did single-celled organisms first come together to form multicellular ones? And how might scientists soon be prepared to build on the basic principles of cell biology to build similar living cells from scratch.
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Author: Bruce Alberts

Publisher: Garland Science

ISBN: 1317563743

Category: Science

Page: 1464

View: 4829

As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced.Protein structures better illustrate structure–function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting “What We Don’t Know,” introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.
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Author: David Boal

Publisher: Cambridge University Press

ISBN: 1139501771

Category: Science

Page: N.A

View: 1417

Exploring the mechanical features of biological cells, including their architecture and stability, this textbook is a pedagogical introduction to the interdisciplinary fields of cell mechanics and soft matter physics from both experimental and theoretical perspectives. This second edition has been greatly updated and expanded, with new chapters on complex filaments, the cell division cycle, the mechanisms of control and organization in the cell, and fluctuation phenomena. The textbook is now in full color which enhances the diagrams and allows the inclusion of new microscopy images. With around 280 end-of-chapter exercises exploring further applications, this textbook is ideal for advanced undergraduate and graduate students in physics and biomedical engineering. A website hosted by the author contains extra support material, diagrams and lecture notes, and is available at www.cambridge.org/Boal.
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The Simple Mechanics of Making More and Working Less

Author: Sam Carpenter

Publisher: Greenleaf Book Group

ISBN: 160832253X

Category: Business & Economics

Page: 250

View: 2644

Work The System aims to convince people to change their fundamental perception of the world around them from a vision of an impenetrable, amorphous conglomeration, to one made up of individual linear systems, each of which can be improved and perfected. The reader is guided through the process of ''getting'' this new vision, and then through the specifics of applying it. It's simple, believable, and mechanical; not mystical or theoretical. Work the System will show business leaders and professionals how to achieve a positive macro result by looking at their business and work on a micro level - by analyzing and refining each of the systems that are already in place. Readers will learn how to tweak this network of systems to maximize profits, create client loyalty, and develop autonomous employees. The strategies will also help individuals improve their performance and decrease the stress of being overtaxed or disorganized.
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How Chemistry Becomes Biology

Author: Addy Pross

Publisher: Oxford University Press

ISBN: 0198784791

Category:

Page: 224

View: 1356

Seventy years ago, Erwin Schrodinger posed a profound question: 'What is life, and how did it emerge from non-life?' This problem has puzzled biologists and physical scientists ever since. Living things are hugely complex and have unique properties, such as self-maintenance and apparently purposeful behaviour which we do not see in inert matter. So how does chemistry give rise to biology? What could have led the first replicating molecules up such a path? Now, developments in the emerging field of 'systems chemistry' are unlocking the problem. Addy Pross shows how the different kind of stability that operates among replicating molecules results in a tendency for chemical systems to become more complex and acquire the properties of life. Strikingly, he demonstrates that Darwinian evolution is the biological expression of a deeper, well-defined chemical concept: the whole story from replicating molecules to complex life is one continuous process governed by an underlying physical principle. The gulf between biology and the physical sciences is finally becoming bridged. This new edition includes an Epilogue describing developments in the concepts of fundamental forms of stability discussed in the book, and their profound implications. Oxford Landmark Science books are 'must-read' classics of modern science writing which have crystallized big ideas, and shaped the way we think.
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The Evolution of Life's Building Blocks

Author: Franklin M. Harold

Publisher: University of Chicago Press

ISBN: 022617431X

Category: Science

Page: 304

View: 7478

The origin of cells remains one of the most fundamental problems in biology, one that over the past two decades has spawned a large body of research and debate. With In Search of Cell History, Franklin M. Harold offers a comprehensive, impartial take on that research and the controversies that keep the field in turmoil. Written in accessible language and complemented by a glossary for easy reference, this book investigates the full scope of cellular history. Assuming only a basic knowledge of cell biology, Harold examines such pivotal subjects as the relationship between cells and genes; the central role of bioenergetics in the origin of life; the status of the universal tree of life with its three stems and viral outliers; and the controversies surrounding the last universal common ancestor. He also delves deeply into the evolution of cellular organization, the origin of complex cells, and the incorporation of symbiotic organelles, and considers the fossil evidence for the earliest life on earth. In Search of Cell History shows us just how far we have come in understanding cell evolution—and the evolution of life in general—and how far we still have to go.
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Discovering the Microscopic World that Determines Our Health, Our Consciousness, and Our Future

Author: Joshua Z. Rappoport

Publisher: BenBella Books, Inc.

ISBN: 1944648976

Category: Science

Page: 272

View: 7589

Your body has trillions of cells, and each one has the complexity and dynamism of a city. Your life, your thoughts, your diseases, and your health are all the function of cells. But what do you really know about what goes on inside you? The last time most people thought about cells in any detail was probably in high school or a college general biology class. But the field of cell biology has advanced incredibly rapidly in recent decades, and a great deal of what we may have learned in high school and college is no longer accurate or particularly relevant. The Cell: Inside the Microscopic World that Determines Our Health, Our Consciousness, and Our Future is a fascinating story of the incredible complexity and dynamism inside the cell and of the fantastic advancements in our understanding of this microscopic world. Dr. Joshua Z. Rappoport is at the forefront of this field, and he will take you on a journey to discover: A deeper understanding of how cells work and the basic nature of life on earth. Fascinating histories of some of the key discoveries from the seventeenth century to the last decade and provocative thoughts on the current state of academic research. The knowledge required to better understand the new developments that are announced almost weekly in science and health care, such as cancer, cellular therapies, and the potential promise of stem cells. The ability to make better decisions about health and to debunk the misinformation that comes in daily via media. Using the latest scientific research, The Cell illustrates the diversity of cell biology and what it all means for your everyday life.
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A Novel

Author: Kate Atkinson

Publisher: Reagan Arthur Books

ISBN: 0316230804

Category: Fiction

Page: 544

View: 9093

What if you could live again and again, until you got it right? On a cold and snowy night in 1910, Ursula Todd is born to an English banker and his wife. She dies before she can draw her first breath. On that same cold and snowy night, Ursula Todd is born, lets out a lusty wail, and embarks upon a life that will be, to say the least, unusual. For as she grows, she also dies, repeatedly, in a variety of ways, while the young century marches on towards its second cataclysmic world war. Does Ursula's apparently infinite number of lives give her the power to save the world from its inevitable destiny? And if she can -- will she? Darkly comic, startlingly poignant, and utterly original -- this is Kate Atkinson at her absolute best.
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Author: Alasdair C. Steven,Wolfgang Baumeister,Louise N. Johnson,Richard N. Perham

Publisher: Garland Science

ISBN: 1134982828

Category: Science

Page: 888

View: 774

Molecular Biology of Assemblies and Machines presents a comprehensive narrative describing the structures of macromolecular complexes and how they assemble and interact. Richly illustrated, it is written for advanced undergraduates, graduate students, and researchers in biochemistry, structural biology, molecular biology, biophysics, cell biology, and microbiology, and will also appeal to those in chemistry, immunology, and medicine. Essentially all major biological activities are performed by assemblies of macromolecules (proteins, RNA, and DNA) acting in concert. These assemblies are dynamic and many are endowed with machine-like properties. This unique book explores the molecular mechanisms employed at the critical level between individual macromolecules and cells and organelles.
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